STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHANK3SH3 and multiple ankyrin repeat domains 3. (1644 aa)    
Predicted Functional Partners:
DLGAP3
DLG associated protein 3.
   
 0.934
DLGAP2
DLG associated protein 2.
   
 0.928
DLGAP4
DLG associated protein 4.
    
 0.807
NLGN3
Neuroligin 3.
   
 0.800
HOMER1
Homer scaffold protein 1.
    
 0.796
FMR1
Fragile X mental retardation 1.
    
 
 0.752
MECP2
Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
      
 0.751
SHANK1
SH3 and multiple ankyrin repeat domains 1.
  
 
0.733
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.717
DLGAP1
DLG associated protein 1.
    
 0.699
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.