STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPP1Secreted phosphoprotein 1. (298 aa)    
Predicted Functional Partners:
CD44
CD44 molecule (Indian blood group).
   
 0.995
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.985
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.969
ITGA9
Integrin subunit alpha 9; Belongs to the integrin alpha chain family.
   
 0.966
ITGAV
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
   
 0.961
ITGA4
Integrin subunit alpha 4; Belongs to the integrin alpha chain family.
   
 0.952
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.944
IRF7
Interferon regulatory factor 7.
   
 0.921
CGA
Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
     
  0.900
MMP7
Matrix metallopeptidase 7.
     
 0.879
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.