STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB5BRAB5B, member RAS oncogene family. (217 aa)    
Predicted Functional Partners:
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.954
RIN1
Ras and Rab interactor 1.
    
 0.933
RAB5C
Uncharacterized protein.
  
  
0.930
KCTD7
Uncharacterized protein.
   
 0.929
RAB5A
RAB5A, member RAS oncogene family.
  
  
 
0.921
EEA1
Early endosome antigen 1.
    
 0.889
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
 0.818
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
 
 0.816
GAPVD1
GTPase activating protein and VPS9 domains 1.
    
 0.806
RBSN
Rabenosyn, RAB effector.
   
 0.777
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.