PRLR protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

PRLR

Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (625 aa)

Predicted Functional Partners:

PRL

0.997

JAK2

0.993

G1MLY5_AILME

0.939

GH1

0.933

JAK3

0.925

CISH

0.917

LEP

0.906

JAK1

0.903

TYK2

0.831

CNTF

0.773

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CISH	G1MLY5_AILME	ENSAMEP00000012131	ENSAMEP00000020373	Cytokine inducible SH2 containing protein.	FERM_F1 domain-containing protein.	0.409
CISH	JAK2	ENSAMEP00000012131	ENSAMEP00000010263	Cytokine inducible SH2 containing protein.	Tyrosine-protein kinase.	0.409
CISH	PRLR	ENSAMEP00000012131	ENSAMEP00000003404	Cytokine inducible SH2 containing protein.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.917
CNTF	G1MLY5_AILME	ENSAMEP00000000859	ENSAMEP00000020373	Ciliary neurotrophic factor.	FERM_F1 domain-containing protein.	0.406
CNTF	GH1	ENSAMEP00000000859	ENSAMEP00000003203	Ciliary neurotrophic factor.	Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity); Belongs to the somatotropin/prolactin family.	0.900
CNTF	JAK1	ENSAMEP00000000859	ENSAMEP00000015988	Ciliary neurotrophic factor.	Tyrosine-protein kinase.	0.402
CNTF	JAK2	ENSAMEP00000000859	ENSAMEP00000010263	Ciliary neurotrophic factor.	Tyrosine-protein kinase.	0.406
CNTF	LEP	ENSAMEP00000000859	ENSAMEP00000005031	Ciliary neurotrophic factor.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.933
CNTF	PRL	ENSAMEP00000000859	ENSAMEP00000011769	Ciliary neurotrophic factor.	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	0.903
CNTF	PRLR	ENSAMEP00000000859	ENSAMEP00000003404	Ciliary neurotrophic factor.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.773
G1MLY5_AILME	CISH	ENSAMEP00000020373	ENSAMEP00000012131	FERM_F1 domain-containing protein.	Cytokine inducible SH2 containing protein.	0.409
G1MLY5_AILME	CNTF	ENSAMEP00000020373	ENSAMEP00000000859	FERM_F1 domain-containing protein.	Ciliary neurotrophic factor.	0.406
G1MLY5_AILME	GH1	ENSAMEP00000020373	ENSAMEP00000003203	FERM_F1 domain-containing protein.	Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity); Belongs to the somatotropin/prolactin family.	0.714
G1MLY5_AILME	JAK1	ENSAMEP00000020373	ENSAMEP00000015988	FERM_F1 domain-containing protein.	Tyrosine-protein kinase.	0.892
G1MLY5_AILME	JAK3	ENSAMEP00000020373	ENSAMEP00000011425	FERM_F1 domain-containing protein.	Tyrosine-protein kinase.	0.415
G1MLY5_AILME	LEP	ENSAMEP00000020373	ENSAMEP00000005031	FERM_F1 domain-containing protein.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.727
G1MLY5_AILME	PRL	ENSAMEP00000020373	ENSAMEP00000011769	FERM_F1 domain-containing protein.	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	0.657
G1MLY5_AILME	PRLR	ENSAMEP00000020373	ENSAMEP00000003404	FERM_F1 domain-containing protein.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.939
G1MLY5_AILME	TYK2	ENSAMEP00000020373	ENSAMEP00000012301	FERM_F1 domain-containing protein.	Tyrosine-protein kinase.	0.896
GH1	CNTF	ENSAMEP00000003203	ENSAMEP00000000859	Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity); Belongs to the somatotropin/prolactin family.	Ciliary neurotrophic factor.	0.900