RFC1 protein (Ailuropoda melanoleuca) - STRING interaction network

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[Homology]

Score

RFC1

Replication factor C subunit 1. (1133 aa)

Predicted Functional Partners:

RFC4

0.998

RFC3

0.997

RFC2

0.997

RFC5

0.997

PCNA

0.988

POLA2

0.952

RPA1

0.950

BLM

0.901

RAD17

0.897

FEN1

0.896

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLM	FEN1	ENSAMEP00000014621	ENSAMEP00000021025	BLM RecQ like helicase.	Flap structure-specific endonuclease 1.	0.811
BLM	PCNA	ENSAMEP00000014621	ENSAMEP00000009571	BLM RecQ like helicase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.781
BLM	RAD17	ENSAMEP00000014621	ENSAMEP00000003427	BLM RecQ like helicase.	RAD17 checkpoint clamp loader component.	0.883
BLM	RFC1	ENSAMEP00000014621	ENSAMEP00000003431	BLM RecQ like helicase.	Replication factor C subunit 1.	0.901
BLM	RFC2	ENSAMEP00000014621	ENSAMEP00000016246	BLM RecQ like helicase.	Replication factor C subunit 2.	0.703
BLM	RFC3	ENSAMEP00000014621	ENSAMEP00000009724	BLM RecQ like helicase.	Replication factor C subunit 3.	0.673
BLM	RFC4	ENSAMEP00000014621	ENSAMEP00000000997	BLM RecQ like helicase.	Replication factor C subunit 4.	0.716
BLM	RFC5	ENSAMEP00000014621	ENSAMEP00000017097	BLM RecQ like helicase.	Replication factor C subunit 5.	0.581
BLM	RPA1	ENSAMEP00000014621	ENSAMEP00000008180	BLM RecQ like helicase.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.995
FEN1	BLM	ENSAMEP00000021025	ENSAMEP00000014621	Flap structure-specific endonuclease 1.	BLM RecQ like helicase.	0.811
FEN1	PCNA	ENSAMEP00000021025	ENSAMEP00000009571	Flap structure-specific endonuclease 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.998
FEN1	POLA2	ENSAMEP00000021025	ENSAMEP00000018585	Flap structure-specific endonuclease 1.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.776
FEN1	RAD17	ENSAMEP00000021025	ENSAMEP00000003427	Flap structure-specific endonuclease 1.	RAD17 checkpoint clamp loader component.	0.835
FEN1	RFC1	ENSAMEP00000021025	ENSAMEP00000003431	Flap structure-specific endonuclease 1.	Replication factor C subunit 1.	0.896
FEN1	RFC2	ENSAMEP00000021025	ENSAMEP00000016246	Flap structure-specific endonuclease 1.	Replication factor C subunit 2.	0.914
FEN1	RFC3	ENSAMEP00000021025	ENSAMEP00000009724	Flap structure-specific endonuclease 1.	Replication factor C subunit 3.	0.943
FEN1	RFC4	ENSAMEP00000021025	ENSAMEP00000000997	Flap structure-specific endonuclease 1.	Replication factor C subunit 4.	0.933
FEN1	RFC5	ENSAMEP00000021025	ENSAMEP00000017097	Flap structure-specific endonuclease 1.	Replication factor C subunit 5.	0.832
FEN1	RPA1	ENSAMEP00000021025	ENSAMEP00000008180	Flap structure-specific endonuclease 1.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.906
PCNA	BLM	ENSAMEP00000009571	ENSAMEP00000014621	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	BLM RecQ like helicase.	0.781