IGFBP5 protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

IGFBP5

Insulin like growth factor binding protein 5. (273 aa)

Predicted Functional Partners:

G1LIG6_AILME

0.918

IGF1

0.918

IGF2

0.880

PAPPA

0.818

PAPPA2

0.676

FAM20C

0.545

INS-IGF2

0.518

LUM

0.494

IGFBP7

0.482

ALX1

0.455

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALX1	IGFBP5	ENSAMEP00000009512	ENSAMEP00000003543	ALX homeobox 1.	Insulin like growth factor binding protein 5.	0.455
FAM20C	IGFBP5	ENSAMEP00000003110	ENSAMEP00000003543	FAM20C golgi associated secretory pathway kinase.	Insulin like growth factor binding protein 5.	0.545
G1LIG6_AILME	IGF2	ENSAMEP00000006719	ENSAMEP00000002277	IlGF domain-containing protein.	Insulin like growth factor 2.	0.532
G1LIG6_AILME	IGFBP5	ENSAMEP00000006719	ENSAMEP00000003543	IlGF domain-containing protein.	Insulin like growth factor binding protein 5.	0.918
G1LIG6_AILME	IGFBP7	ENSAMEP00000006719	ENSAMEP00000009052	IlGF domain-containing protein.	Insulin like growth factor binding protein 7.	0.673
G1LIG6_AILME	INS-IGF2	ENSAMEP00000006719	ENSAMEP00000002279	IlGF domain-containing protein.	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.638
G1LIG6_AILME	PAPPA	ENSAMEP00000006719	ENSAMEP00000013048	IlGF domain-containing protein.	Pappalysin 1.	0.502
IGF1	IGF2	ENSAMEP00000006724	ENSAMEP00000002277	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor 2.	0.951
IGF1	IGFBP5	ENSAMEP00000006724	ENSAMEP00000003543	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 5.	0.918
IGF1	IGFBP7	ENSAMEP00000006724	ENSAMEP00000009052	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 7.	0.673
IGF1	INS-IGF2	ENSAMEP00000006724	ENSAMEP00000002279	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.962
IGF1	PAPPA	ENSAMEP00000006724	ENSAMEP00000013048	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Pappalysin 1.	0.502
IGF2	G1LIG6_AILME	ENSAMEP00000002277	ENSAMEP00000006719	Insulin like growth factor 2.	IlGF domain-containing protein.	0.532
IGF2	IGF1	ENSAMEP00000002277	ENSAMEP00000006724	Insulin like growth factor 2.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.951
IGF2	IGFBP5	ENSAMEP00000002277	ENSAMEP00000003543	Insulin like growth factor 2.	Insulin like growth factor binding protein 5.	0.880
IGF2	IGFBP7	ENSAMEP00000002277	ENSAMEP00000009052	Insulin like growth factor 2.	Insulin like growth factor binding protein 7.	0.472
IGF2	INS-IGF2	ENSAMEP00000002277	ENSAMEP00000002279	Insulin like growth factor 2.	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.706
IGF2	PAPPA	ENSAMEP00000002277	ENSAMEP00000013048	Insulin like growth factor 2.	Pappalysin 1.	0.585
IGF2	PAPPA2	ENSAMEP00000002277	ENSAMEP00000018096	Insulin like growth factor 2.	Pappalysin 2.	0.462
IGFBP5	ALX1	ENSAMEP00000003543	ENSAMEP00000009512	Insulin like growth factor binding protein 5.	ALX homeobox 1.	0.455