MOV10 protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

MOV10

Mov10 RISC complex RNA helicase. (1025 aa)

Predicted Functional Partners:

PIWIL2

0.660

ASZ1

0.635

PLD6

0.609

AGO2

0.589

TDRD5

0.588

UPF1

0.568

G1LQP8_AILME

0.558

PIWIL1

0.555

VPS41

0.552

DDX6

0.534

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	DDX6	ENSAMEP00000005384	ENSAMEP00000006421	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.977
AGO2	MOV10	ENSAMEP00000005384	ENSAMEP00000003752	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Mov10 RISC complex RNA helicase.	0.589
AGO2	UPF1	ENSAMEP00000005384	ENSAMEP00000012088	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	UPF1 RNA helicase and ATPase.	0.616
ASZ1	G1LQP8_AILME	ENSAMEP00000001309	ENSAMEP00000009382	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Uncharacterized protein; Belongs to the argonaute family.	0.499
ASZ1	MOV10	ENSAMEP00000001309	ENSAMEP00000003752	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Mov10 RISC complex RNA helicase.	0.635
ASZ1	PIWIL1	ENSAMEP00000001309	ENSAMEP00000006913	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.	0.499
ASZ1	PIWIL2	ENSAMEP00000001309	ENSAMEP00000003382	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.	0.814
ASZ1	PLD6	ENSAMEP00000001309	ENSAMEP00000002356	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Phospholipase D family member 6.	0.672
ASZ1	TDRD5	ENSAMEP00000001309	ENSAMEP00000015531	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity); Belongs to the TDRD5 family.	0.582
DDX6	AGO2	ENSAMEP00000006421	ENSAMEP00000005384	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.977
DDX6	MOV10	ENSAMEP00000006421	ENSAMEP00000003752	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Mov10 RISC complex RNA helicase.	0.534
DDX6	UPF1	ENSAMEP00000006421	ENSAMEP00000012088	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	UPF1 RNA helicase and ATPase.	0.794
G1LQP8_AILME	ASZ1	ENSAMEP00000009382	ENSAMEP00000001309	Uncharacterized protein; Belongs to the argonaute family.	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	0.499
G1LQP8_AILME	MOV10	ENSAMEP00000009382	ENSAMEP00000003752	Uncharacterized protein; Belongs to the argonaute family.	Mov10 RISC complex RNA helicase.	0.558
G1LQP8_AILME	PLD6	ENSAMEP00000009382	ENSAMEP00000002356	Uncharacterized protein; Belongs to the argonaute family.	Phospholipase D family member 6.	0.708
G1LQP8_AILME	TDRD5	ENSAMEP00000009382	ENSAMEP00000015531	Uncharacterized protein; Belongs to the argonaute family.	Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity); Belongs to the TDRD5 family.	0.646
MOV10	AGO2	ENSAMEP00000003752	ENSAMEP00000005384	Mov10 RISC complex RNA helicase.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.589
MOV10	ASZ1	ENSAMEP00000003752	ENSAMEP00000001309	Mov10 RISC complex RNA helicase.	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	0.635
MOV10	DDX6	ENSAMEP00000003752	ENSAMEP00000006421	Mov10 RISC complex RNA helicase.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.534
MOV10	G1LQP8_AILME	ENSAMEP00000003752	ENSAMEP00000009382	Mov10 RISC complex RNA helicase.	Uncharacterized protein; Belongs to the argonaute family.	0.558