STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK2Serine/threonine-protein kinase PLK. (685 aa)    
Predicted Functional Partners:
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.855
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.777
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.772
RAD21
RAD21 cohesin complex component.
   
 0.767
RAD21L1
Double-strand-break repair protein rad21-like protein 1; Meiosis-specific component of some cohesin complex required during the initial steps of prophase I in male meiosis. Probably required during early meiosis in males for separation of sister chromatids and homologous chromosomes. Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I. Involved in synaptonemal complex assembly, synapsis initiation and crossover recombination between homologous chromosomes during prophase I (By similarity).
   
 0.767
KIF23
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.763
BUB1B
BUB1 N-terminal domain-containing protein.
   
 0.760
SMC3
Structural maintenance of chromosomes protein.
   
 0.757
ITSN2
Intersectin 2.
    
 0.740
CDC20
Cell division cycle 20.
   
 0.739
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.