STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFKBIZNFKB inhibitor zeta. (722 aa)    
Predicted Functional Partners:
RELA
RELA proto-oncogene, NF-kB subunit.
   
 0.930
NFKB1
Uncharacterized protein.
   
0.912
TNFAIP3
TNF alpha induced protein 3.
   
 
 0.655
ZC3H12A
Zinc finger CCCH-type containing 12A.
   
 
 0.579
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
   
 0.540
RELB
RELB proto-oncogene, NF-kB subunit.
   
 0.536
IL1A
Interleukin-1; Belongs to the IL-1 family.
   
 
 0.521
IRF1
Interferon regulatory factor 1.
   
 0.516
NFKBIB
NFKB inhibitor beta.
  
   
0.490
IL1B
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
   
 
 0.488
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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