NUDT15 protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

NUDT15

Nudix hydrolase 15. (171 aa)

Predicted Functional Partners:

NADSYN1

0.919

FPGS

0.893

QPRT

0.890

GCH1

0.880

G1MA08_AILME

0.880

NAPRT

0.867

MROH6

0.867

NUDT18

0.853

TYMS

0.846

G1LK61_AILME

0.846

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FPGS	G1LK61_AILME	ENSAMEP00000015884	ENSAMEP00000007321	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Thymidylat_synt domain-containing protein.	0.885
FPGS	G1MA08_AILME	ENSAMEP00000015884	ENSAMEP00000016181	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	GTP_cyclohydroI domain-containing protein.	0.603
FPGS	GCH1	ENSAMEP00000015884	ENSAMEP00000015186	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	GTP_cyclohydroI domain-containing protein.	0.603
FPGS	NADSYN1	ENSAMEP00000015884	ENSAMEP00000007956	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.451
FPGS	NUDT15	ENSAMEP00000015884	ENSAMEP00000003940	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Nudix hydrolase 15.	0.893
FPGS	TYMS	ENSAMEP00000015884	ENSAMEP00000006970	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Thymidylat_synt domain-containing protein.	0.976
G1LK61_AILME	FPGS	ENSAMEP00000007321	ENSAMEP00000015884	Thymidylat_synt domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.885
G1LK61_AILME	NUDT15	ENSAMEP00000007321	ENSAMEP00000003940	Thymidylat_synt domain-containing protein.	Nudix hydrolase 15.	0.846
G1MA08_AILME	FPGS	ENSAMEP00000016181	ENSAMEP00000015884	GTP_cyclohydroI domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.603
G1MA08_AILME	GCH1	ENSAMEP00000016181	ENSAMEP00000015186	GTP_cyclohydroI domain-containing protein.	GTP_cyclohydroI domain-containing protein.	0.755
G1MA08_AILME	NUDT15	ENSAMEP00000016181	ENSAMEP00000003940	GTP_cyclohydroI domain-containing protein.	Nudix hydrolase 15.	0.880
GCH1	FPGS	ENSAMEP00000015186	ENSAMEP00000015884	GTP_cyclohydroI domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.603
GCH1	G1MA08_AILME	ENSAMEP00000015186	ENSAMEP00000016181	GTP_cyclohydroI domain-containing protein.	GTP_cyclohydroI domain-containing protein.	0.755
GCH1	NUDT15	ENSAMEP00000015186	ENSAMEP00000003940	GTP_cyclohydroI domain-containing protein.	Nudix hydrolase 15.	0.880
MROH6	NADSYN1	ENSAMEP00000006979	ENSAMEP00000007956	Maestro heat like repeat family member 6.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.645
MROH6	NUDT15	ENSAMEP00000006979	ENSAMEP00000003940	Maestro heat like repeat family member 6.	Nudix hydrolase 15.	0.867
MROH6	QPRT	ENSAMEP00000006979	ENSAMEP00000008444	Maestro heat like repeat family member 6.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.502
NADSYN1	FPGS	ENSAMEP00000007956	ENSAMEP00000015884	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.451
NADSYN1	MROH6	ENSAMEP00000007956	ENSAMEP00000006979	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Maestro heat like repeat family member 6.	0.645
NADSYN1	NAPRT	ENSAMEP00000007956	ENSAMEP00000006971	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.780