STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX58DExD/H-box helicase 58. (931 aa)    
Predicted Functional Partners:
MAVS
Mitochondrial antiviral signaling protein.
    
 0.998
ISG15
ISG15 ubiquitin like modifier.
   
 0.993
OASL
Uncharacterized protein.
   
 0.985
TRIM25
Tripartite motif containing 25.
   
 0.982
DHX58
DExH-box helicase 58.
   
0.979
ATG5
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 0.953
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.953
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.953
ATG12
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
    
 0.953
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 0.939
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.