| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSKMT | EEF1AKMT2 | ENSAMEP00000006856 | ENSAMEP00000004419 | Citrate synthase lysine methyltransferase. | Methyltranfer_dom domain-containing protein. | 0.605 |
| CSKMT | METTL16 | ENSAMEP00000006856 | ENSAMEP00000007935 | Citrate synthase lysine methyltransferase. | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | 0.447 |
| EEF1AKMT1 | EEF1AKMT2 | ENSAMEP00000015526 | ENSAMEP00000004419 | EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family. | Methyltranfer_dom domain-containing protein. | 0.622 |
| EEF1AKMT2 | CSKMT | ENSAMEP00000004419 | ENSAMEP00000006856 | Methyltranfer_dom domain-containing protein. | Citrate synthase lysine methyltransferase. | 0.605 |
| EEF1AKMT2 | EEF1AKMT1 | ENSAMEP00000004419 | ENSAMEP00000015526 | Methyltranfer_dom domain-containing protein. | EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family. | 0.622 |
| EEF1AKMT2 | METTL16 | ENSAMEP00000004419 | ENSAMEP00000007935 | Methyltranfer_dom domain-containing protein. | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | 0.749 |
| EEF1AKMT2 | METTL21C | ENSAMEP00000004419 | ENSAMEP00000017433 | Methyltranfer_dom domain-containing protein. | Methyltransferase like 21C. | 0.711 |
| EEF1AKMT2 | METTL25 | ENSAMEP00000004419 | ENSAMEP00000017821 | Methyltranfer_dom domain-containing protein. | Methyltransferase like 25. | 0.923 |
| EEF1AKMT2 | METTL5 | ENSAMEP00000004419 | ENSAMEP00000011036 | Methyltranfer_dom domain-containing protein. | Methyltransferase like 5. | 0.804 |
| EEF1AKMT2 | METTL7B | ENSAMEP00000004419 | ENSAMEP00000012546 | Methyltranfer_dom domain-containing protein. | Methyltransferase like 7B. | 0.845 |
| EEF1AKMT2 | METTL8 | ENSAMEP00000004419 | ENSAMEP00000009104 | Methyltranfer_dom domain-containing protein. | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | 0.839 |
| EEF1AKMT2 | NTMT1 | ENSAMEP00000004419 | ENSAMEP00000016883 | Methyltranfer_dom domain-containing protein. | N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed; Distributive alpha-N-methyltransferase that methylates the N- terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]- Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Catalyzes the trimethylation of the N-terminal Gly [...] | 0.631 |
| EEF1AKMT2 | ZCCHC4 | ENSAMEP00000004419 | ENSAMEP00000019145 | Methyltranfer_dom domain-containing protein. | Uncharacterized protein. | 0.631 |
| METTL16 | CSKMT | ENSAMEP00000007935 | ENSAMEP00000006856 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Citrate synthase lysine methyltransferase. | 0.447 |
| METTL16 | EEF1AKMT2 | ENSAMEP00000007935 | ENSAMEP00000004419 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Methyltranfer_dom domain-containing protein. | 0.749 |
| METTL16 | METTL25 | ENSAMEP00000007935 | ENSAMEP00000017821 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Methyltransferase like 25. | 0.651 |
| METTL16 | METTL5 | ENSAMEP00000007935 | ENSAMEP00000011036 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Methyltransferase like 5. | 0.762 |
| METTL16 | METTL8 | ENSAMEP00000007935 | ENSAMEP00000009104 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. | 0.498 |
| METTL16 | NTMT1 | ENSAMEP00000007935 | ENSAMEP00000016883 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed; Distributive alpha-N-methyltransferase that methylates the N- terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]- Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Catalyzes the trimethylation of the N-terminal Gly [...] | 0.529 |
| METTL16 | ZCCHC4 | ENSAMEP00000007935 | ENSAMEP00000019145 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] | Uncharacterized protein. | 0.642 |