STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLXDC1Plexin domain containing 1. (476 aa)    
Predicted Functional Partners:
KIAA1755
KIAA1755.
      
 0.579
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.
      
 0.576
MTMR10
Myotubularin related protein 10.
      
 0.521
ADGRD1
Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.
      
 0.512
COMMD10
COMM domain containing 10.
      
 0.502
LY6G6C
Lymphocyte antigen 6 family member G6C.
      
 0.481
CCDC3
Coiled-coil domain containing 3.
      
 0.447
RPRML
Reprimo like.
      
 0.439
MMP27
Matrix metallopeptidase 27.
      
 0.436
MED13
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.432
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.