STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL11Oxysterol-binding protein; Belongs to the OSBP family. (750 aa)    
Predicted Functional Partners:
G1LBF0_AILME
Uncharacterized protein.
    
  
0.775
KLHL25
Kelch like family member 25.
    
 
 0.648
PLXNB3
Plexin B3.
   
  
 0.633
RNF152
E3 ubiquitin-protein ligase RNF152; E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed. Belongs to the RNF152 family.
      
 0.620
NME6
Nucleoside diphosphate kinase.
   
  
 0.617
STT3B
STT3 oligosaccharyltransferase complex catalytic subunit B.
   
  
 0.613
CHODL
Chondrolectin.
      
 0.576
AKAP13
A-kinase anchoring protein 13.
   
  
 0.565
PLXNB1
Plexin B1.
   
  
 0.532
SLC39A6
Solute carrier family 39 member 6.
      
 0.531
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.