STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIT1GIT ArfGAP 1. (773 aa)    
Predicted Functional Partners:
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.990
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.990
GRK2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    
 
 0.895
PAK3
P21 (RAC1) activated kinase 3.
    
 0.867
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.832
GIT2
GIT ArfGAP 2.
  
 
0.806
WASF1
WASP family member 1.
     
 0.768
ITSN2
Intersectin 2.
   
 
 0.753
GRK3
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    
 
 0.751
ROBO4
Roundabout guidance receptor 4.
      
 0.745
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.