STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF1Rho guanine nucleotide exchange factor 1. (934 aa)    
Predicted Functional Partners:
GNA13
G protein subunit alpha 13.
    
 0.987
GNA12
G protein subunit alpha 12.
    
 0.814
RHOC
Ras homolog family member C.
   
 0.785
RHOA
Ras homolog family member A.
   
 0.785
RHOB
Ras homolog family member B.
   
 0.785
MKNK2
MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily.
      
 0.630
GNAT1
G protein subunit alpha transducin 1.
    
 0.626
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.610
P2RY8
P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family.
      
 0.610
AP3M1
Adaptor related protein complex 3 subunit mu 1; Belongs to the adaptor complexes medium subunit family.
      
 0.604
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.