IL12RB2 protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

IL12RB2

Interleukin 12 receptor subunit beta 2. (863 aa)

Predicted Functional Partners:

IL12RB1

0.992

TYK2

0.968

JAK2

0.964

IL12A

0.951

IL12B

0.943

JAK3

0.855

LIF

0.850

JAK1

0.847

IFNG

0.842

CNTF

0.808

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTF	IL12RB1	ENSAMEP00000000859	ENSAMEP00000011576	Ciliary neurotrophic factor.	Interleukin 12 receptor subunit beta 1.	0.652
CNTF	IL12RB2	ENSAMEP00000000859	ENSAMEP00000004845	Ciliary neurotrophic factor.	Interleukin 12 receptor subunit beta 2.	0.808
CNTF	JAK1	ENSAMEP00000000859	ENSAMEP00000015988	Ciliary neurotrophic factor.	Tyrosine-protein kinase.	0.402
CNTF	JAK2	ENSAMEP00000000859	ENSAMEP00000010263	Ciliary neurotrophic factor.	Tyrosine-protein kinase.	0.406
CNTF	LIF	ENSAMEP00000000859	ENSAMEP00000008318	Ciliary neurotrophic factor.	LIF interleukin 6 family cytokine.	0.684
IFNG	IL12A	ENSAMEP00000009180	ENSAMEP00000003323	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.	0.636
IFNG	IL12B	ENSAMEP00000009180	ENSAMEP00000006903	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	0.579
IFNG	IL12RB1	ENSAMEP00000009180	ENSAMEP00000011576	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Interleukin 12 receptor subunit beta 1.	0.786
IFNG	IL12RB2	ENSAMEP00000009180	ENSAMEP00000004845	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Interleukin 12 receptor subunit beta 2.	0.842
IFNG	JAK1	ENSAMEP00000009180	ENSAMEP00000015988	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Tyrosine-protein kinase.	0.983
IFNG	JAK2	ENSAMEP00000009180	ENSAMEP00000010263	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Tyrosine-protein kinase.	0.973
IFNG	JAK3	ENSAMEP00000009180	ENSAMEP00000011425	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Tyrosine-protein kinase.	0.635
IFNG	LIF	ENSAMEP00000009180	ENSAMEP00000008318	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	LIF interleukin 6 family cytokine.	0.435
IFNG	TYK2	ENSAMEP00000009180	ENSAMEP00000012301	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Tyrosine-protein kinase.	0.743
IL12A	IFNG	ENSAMEP00000003323	ENSAMEP00000009180	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	0.636
IL12A	IL12B	ENSAMEP00000003323	ENSAMEP00000006903	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	0.994
IL12A	IL12RB1	ENSAMEP00000003323	ENSAMEP00000011576	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.	Interleukin 12 receptor subunit beta 1.	0.952
IL12A	IL12RB2	ENSAMEP00000003323	ENSAMEP00000004845	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.	Interleukin 12 receptor subunit beta 2.	0.951
IL12B	IFNG	ENSAMEP00000006903	ENSAMEP00000009180	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	0.579
IL12B	IL12A	ENSAMEP00000006903	ENSAMEP00000003323	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.	0.994