STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D2TBC1 domain family member 2A; Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion (By similarity). (934 aa)    
Predicted Functional Partners:
RAB7A
RAB7A, member RAS oncogene family.
    
 0.931
TBC1D21
TBC1 domain family member 21.
      
 0.751
TBC1D13
TBC1 domain family member 13.
      
 0.750
TBC1D19
TBC1 domain family member 19.
      
 0.740
TBC1D7
TBC1 domain family member 7.
      
 0.682
CCZ1
Uncharacterized protein.
      
 0.613
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2.
      
 0.609
RILP
Rab interacting lysosomal protein.
      
 0.583
TBC1D20
TBC1 domain family member 20.
   
  
 0.540
TBC1D5
TBC1 domain family member 5.
   
  
 0.535
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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