PAX4 protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PAX4

Paired box 4. (346 aa)

Predicted Functional Partners:

INS-IGF2

0.814

SUZ12

0.785

FAP

0.780

TIMM22

0.737

INSM1

0.730

NEUROG2

0.707

NEUROG3

0.707

PCSK1

0.705

SLC30A8

0.700

MAF

0.660

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAP	INS-IGF2	ENSAMEP00000006000	ENSAMEP00000002279	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.830
FAP	MAF	ENSAMEP00000006000	ENSAMEP00000010869	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	BZIP domain-containing protein; Belongs to the bZIP family.	0.571
FAP	NEUROG2	ENSAMEP00000006000	ENSAMEP00000016469	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	Neurogenin 2.	0.529
FAP	NEUROG3	ENSAMEP00000006000	ENSAMEP00000020103	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	Neurogenin 3.	0.529
FAP	PAX4	ENSAMEP00000006000	ENSAMEP00000004910	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	Paired box 4.	0.780
FAP	PCSK1	ENSAMEP00000006000	ENSAMEP00000019269	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.777
FAP	SLC30A8	ENSAMEP00000006000	ENSAMEP00000001719	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	Solute carrier family 30 member 8.	0.616
INS-IGF2	FAP	ENSAMEP00000002279	ENSAMEP00000006000	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	0.830
INS-IGF2	MAF	ENSAMEP00000002279	ENSAMEP00000010869	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	BZIP domain-containing protein; Belongs to the bZIP family.	0.640
INS-IGF2	NEUROG2	ENSAMEP00000002279	ENSAMEP00000016469	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenin 2.	0.549
INS-IGF2	NEUROG3	ENSAMEP00000002279	ENSAMEP00000020103	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenin 3.	0.549
INS-IGF2	PAX4	ENSAMEP00000002279	ENSAMEP00000004910	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Paired box 4.	0.814
INS-IGF2	PCSK1	ENSAMEP00000002279	ENSAMEP00000019269	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.811
INS-IGF2	SLC30A8	ENSAMEP00000002279	ENSAMEP00000001719	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Solute carrier family 30 member 8.	0.703
INSM1	NEUROG2	ENSAMEP00000000295	ENSAMEP00000016469	INSM transcriptional repressor 1.	Neurogenin 2.	0.697
INSM1	NEUROG3	ENSAMEP00000000295	ENSAMEP00000020103	INSM transcriptional repressor 1.	Neurogenin 3.	0.697
INSM1	PAX4	ENSAMEP00000000295	ENSAMEP00000004910	INSM transcriptional repressor 1.	Paired box 4.	0.730
MAF	FAP	ENSAMEP00000010869	ENSAMEP00000006000	BZIP domain-containing protein; Belongs to the bZIP family.	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	0.571
MAF	INS-IGF2	ENSAMEP00000010869	ENSAMEP00000002279	BZIP domain-containing protein; Belongs to the bZIP family.	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.640
MAF	NEUROG2	ENSAMEP00000010869	ENSAMEP00000016469	BZIP domain-containing protein; Belongs to the bZIP family.	Neurogenin 2.	0.458