STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLI1GLI family zinc finger 1. (1105 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.998
SPOP
Speckle type BTB/POZ protein.
   
 0.977
SPOPL
Speckle type BTB/POZ protein like.
   
 0.968
GLI3
GLI family zinc finger 3.
     
0.961
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
 0.957
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.950
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 0.950
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.948
PTCH1
Patched 1.
   
 0.945
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.943
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.