| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGBL5 | CEP41 | ENSAMEP00000002036 | ENSAMEP00000005961 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. | Centrosomal protein 41. | 0.603 |
| AGBL5 | TTLL5 | ENSAMEP00000002036 | ENSAMEP00000019387 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. | Tubulin tyrosine ligase like 5. | 0.610 |
| AGBL5 | TTLL6 | ENSAMEP00000002036 | ENSAMEP00000005286 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. | Tubulin tyrosine ligase like 6. | 0.508 |
| CEP41 | AGBL5 | ENSAMEP00000005961 | ENSAMEP00000002036 | Centrosomal protein 41. | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. | 0.603 |
| CEP41 | TTLL6 | ENSAMEP00000005961 | ENSAMEP00000005286 | Centrosomal protein 41. | Tubulin tyrosine ligase like 6. | 0.608 |
| KIF21A | TTLL6 | ENSAMEP00000013697 | ENSAMEP00000005286 | Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Tubulin tyrosine ligase like 6. | 0.470 |
| MLXIPL | OCIAD2 | ENSAMEP00000011867 | ENSAMEP00000008654 | MLX interacting protein like. | OCIA domain containing 2. | 0.495 |
| MLXIPL | TTLL6 | ENSAMEP00000011867 | ENSAMEP00000005286 | MLX interacting protein like. | Tubulin tyrosine ligase like 6. | 0.460 |
| OCIAD2 | MLXIPL | ENSAMEP00000008654 | ENSAMEP00000011867 | OCIA domain containing 2. | MLX interacting protein like. | 0.495 |
| OCIAD2 | TTLL6 | ENSAMEP00000008654 | ENSAMEP00000005286 | OCIA domain containing 2. | Tubulin tyrosine ligase like 6. | 0.514 |
| SIX5 | SNRPD2 | ENSAMEP00000000811 | ENSAMEP00000000843 | Homeobox domain-containing protein. | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. | 0.553 |
| SIX5 | TTLL6 | ENSAMEP00000000811 | ENSAMEP00000005286 | Homeobox domain-containing protein. | Tubulin tyrosine ligase like 6. | 0.469 |
| SIX5 | UBE2Z | ENSAMEP00000000811 | ENSAMEP00000005341 | Homeobox domain-containing protein. | Ubiquitin conjugating enzyme E2 Z. | 0.537 |
| SNRPD2 | SIX5 | ENSAMEP00000000843 | ENSAMEP00000000811 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. | Homeobox domain-containing protein. | 0.553 |
| SNRPD2 | TTLL6 | ENSAMEP00000000843 | ENSAMEP00000005286 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. | Tubulin tyrosine ligase like 6. | 0.502 |
| SNRPD2 | UBE2Z | ENSAMEP00000000843 | ENSAMEP00000005341 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. | Ubiquitin conjugating enzyme E2 Z. | 0.595 |
| SNX11 | TTLL6 | ENSAMEP00000005187 | ENSAMEP00000005286 | Sorting nexin 11. | Tubulin tyrosine ligase like 6. | 0.513 |
| TTLL5 | AGBL5 | ENSAMEP00000019387 | ENSAMEP00000002036 | Tubulin tyrosine ligase like 5. | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. | 0.610 |
| TTLL5 | TTLL6 | ENSAMEP00000019387 | ENSAMEP00000005286 | Tubulin tyrosine ligase like 5. | Tubulin tyrosine ligase like 6. | 0.608 |
| TTLL6 | AGBL5 | ENSAMEP00000005286 | ENSAMEP00000002036 | Tubulin tyrosine ligase like 6. | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. | 0.508 |