| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACLY | ELOVL6 | ENSAMEP00000006186 | ENSAMEP00000015750 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Elongation of very long chain fatty acids protein. | 0.648 |
| ACLY | FASN | ENSAMEP00000006186 | ENSAMEP00000018282 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Fatty acid synthase. | 0.988 |
| ACLY | SCD | ENSAMEP00000006186 | ENSAMEP00000007110 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. | 0.629 |
| ACLY | SCD5 | ENSAMEP00000006186 | ENSAMEP00000005405 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. | 0.525 |
| ELOVL6 | ACLY | ENSAMEP00000015750 | ENSAMEP00000006186 | Elongation of very long chain fatty acids protein. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.648 |
| ELOVL6 | FASN | ENSAMEP00000015750 | ENSAMEP00000018282 | Elongation of very long chain fatty acids protein. | Fatty acid synthase. | 0.820 |
| ELOVL6 | HACD1 | ENSAMEP00000015750 | ENSAMEP00000011162 | Elongation of very long chain fatty acids protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.924 |
| ELOVL6 | HACD2 | ENSAMEP00000015750 | ENSAMEP00000004942 | Elongation of very long chain fatty acids protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.945 |
| ELOVL6 | HACD3 | ENSAMEP00000015750 | ENSAMEP00000003148 | Elongation of very long chain fatty acids protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.913 |
| ELOVL6 | HACD4 | ENSAMEP00000015750 | ENSAMEP00000003175 | Elongation of very long chain fatty acids protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.909 |
| ELOVL6 | SCD | ENSAMEP00000015750 | ENSAMEP00000007110 | Elongation of very long chain fatty acids protein. | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. | 0.962 |
| ELOVL6 | SCD5 | ENSAMEP00000015750 | ENSAMEP00000005405 | Elongation of very long chain fatty acids protein. | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. | 0.930 |
| FASN | ACLY | ENSAMEP00000018282 | ENSAMEP00000006186 | Fatty acid synthase. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.988 |
| FASN | ELOVL6 | ENSAMEP00000018282 | ENSAMEP00000015750 | Fatty acid synthase. | Elongation of very long chain fatty acids protein. | 0.820 |
| FASN | SCD | ENSAMEP00000018282 | ENSAMEP00000007110 | Fatty acid synthase. | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. | 0.883 |
| FASN | SCD5 | ENSAMEP00000018282 | ENSAMEP00000005405 | Fatty acid synthase. | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. | 0.690 |
| GALNT18 | SCD5 | ENSAMEP00000001217 | ENSAMEP00000005405 | Polypeptide N-acetylgalactosaminyltransferase. | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. | 0.504 |
| HACD1 | ELOVL6 | ENSAMEP00000011162 | ENSAMEP00000015750 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Elongation of very long chain fatty acids protein. | 0.924 |
| HACD1 | HACD2 | ENSAMEP00000011162 | ENSAMEP00000004942 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.901 |
| HACD1 | HACD3 | ENSAMEP00000011162 | ENSAMEP00000003148 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.907 |