G1LES5_AILME protein (Ailuropoda melanoleuca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

G1LES5_AILME

Uncharacterized protein. (246 aa)

Predicted Functional Partners:

MTHFSD

0.541

SLC25A44

0.514

SFT2D2

0.491

SFT2D3

0.489

OPTC

0.467

MCFD2

0.457

HIF1AN

0.457

UTP15

0.455

WDR6

0.454

PSMD1

0.454

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1LES5_AILME	HIF1AN	ENSAMEP00000005412	ENSAMEP00000006994	Uncharacterized protein.	Hypoxia inducible factor 1 subunit alpha inhibitor.	0.457
G1LES5_AILME	MCFD2	ENSAMEP00000005412	ENSAMEP00000006420	Uncharacterized protein.	Multiple coagulation factor deficiency 2.	0.457
G1LES5_AILME	MTHFSD	ENSAMEP00000005412	ENSAMEP00000019302	Uncharacterized protein.	Methenyltetrahydrofolate synthetase domain containing.	0.541
G1LES5_AILME	OPTC	ENSAMEP00000005412	ENSAMEP00000000735	Uncharacterized protein.	Opticin.	0.467
G1LES5_AILME	PSMD1	ENSAMEP00000005412	ENSAMEP00000017352	Uncharacterized protein.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.454
G1LES5_AILME	SFT2D2	ENSAMEP00000005412	ENSAMEP00000016341	Uncharacterized protein.	Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.	0.491
G1LES5_AILME	SFT2D3	ENSAMEP00000005412	ENSAMEP00000019619	Uncharacterized protein.	Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.	0.489
G1LES5_AILME	SLC25A44	ENSAMEP00000005412	ENSAMEP00000015173	Uncharacterized protein.	Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.514
G1LES5_AILME	UTP15	ENSAMEP00000005412	ENSAMEP00000012123	Uncharacterized protein.	UTP15 small subunit processome component.	0.455
G1LES5_AILME	WDR6	ENSAMEP00000005412	ENSAMEP00000013695	Uncharacterized protein.	WD repeat domain 6.	0.454
HIF1AN	G1LES5_AILME	ENSAMEP00000006994	ENSAMEP00000005412	Hypoxia inducible factor 1 subunit alpha inhibitor.	Uncharacterized protein.	0.457
MCFD2	G1LES5_AILME	ENSAMEP00000006420	ENSAMEP00000005412	Multiple coagulation factor deficiency 2.	Uncharacterized protein.	0.457
MCFD2	SLC25A44	ENSAMEP00000006420	ENSAMEP00000015173	Multiple coagulation factor deficiency 2.	Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.481
MTHFSD	G1LES5_AILME	ENSAMEP00000019302	ENSAMEP00000005412	Methenyltetrahydrofolate synthetase domain containing.	Uncharacterized protein.	0.541
MTHFSD	PSMD1	ENSAMEP00000019302	ENSAMEP00000017352	Methenyltetrahydrofolate synthetase domain containing.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.650
MTHFSD	UTP15	ENSAMEP00000019302	ENSAMEP00000012123	Methenyltetrahydrofolate synthetase domain containing.	UTP15 small subunit processome component.	0.780
MTHFSD	WDR6	ENSAMEP00000019302	ENSAMEP00000013695	Methenyltetrahydrofolate synthetase domain containing.	WD repeat domain 6.	0.654
OPTC	G1LES5_AILME	ENSAMEP00000000735	ENSAMEP00000005412	Opticin.	Uncharacterized protein.	0.467
PSMD1	G1LES5_AILME	ENSAMEP00000017352	ENSAMEP00000005412	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Uncharacterized protein.	0.454
PSMD1	MTHFSD	ENSAMEP00000017352	ENSAMEP00000019302	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Methenyltetrahydrofolate synthetase domain containing.	0.650