| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASS1 | CAD | ENSAMEP00000017086 | ENSAMEP00000001870 | Argininosuccinate synthase 1. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.904 |
| ASS1 | CPS1 | ENSAMEP00000017086 | ENSAMEP00000005446 | Argininosuccinate synthase 1. | Carbamoyl-phosphate synthase 1. | 0.965 |
| ASS1 | GART | ENSAMEP00000017086 | ENSAMEP00000015701 | Argininosuccinate synthase 1. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.581 |
| ASS1 | GLUD1 | ENSAMEP00000017086 | ENSAMEP00000010544 | Argininosuccinate synthase 1. | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.574 |
| ASS1 | NAGS | ENSAMEP00000017086 | ENSAMEP00000019338 | Argininosuccinate synthase 1. | N-acetylglutamate synthase. | 0.968 |
| ASS1 | OTC | ENSAMEP00000017086 | ENSAMEP00000007534 | Argininosuccinate synthase 1. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.992 |
| CAD | ASS1 | ENSAMEP00000001870 | ENSAMEP00000017086 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Argininosuccinate synthase 1. | 0.904 |
| CAD | CPS1 | ENSAMEP00000001870 | ENSAMEP00000005446 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Carbamoyl-phosphate synthase 1. | 0.902 |
| CAD | DHODH | ENSAMEP00000001870 | ENSAMEP00000002674 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.986 |
| CAD | GART | ENSAMEP00000001870 | ENSAMEP00000015701 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.836 |
| CAD | GLS | ENSAMEP00000001870 | ENSAMEP00000014797 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutaminase. | 0.904 |
| CAD | GLS2 | ENSAMEP00000001870 | ENSAMEP00000004264 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutaminase 2. | 0.903 |
| CAD | GLUD1 | ENSAMEP00000001870 | ENSAMEP00000010544 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.697 |
| CAD | GLUL | ENSAMEP00000001870 | ENSAMEP00000008130 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamine synthetase. | 0.955 |
| CAD | NAGS | ENSAMEP00000001870 | ENSAMEP00000019338 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | N-acetylglutamate synthase. | 0.623 |
| CAD | OTC | ENSAMEP00000001870 | ENSAMEP00000007534 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.973 |
| CPS1 | ASS1 | ENSAMEP00000005446 | ENSAMEP00000017086 | Carbamoyl-phosphate synthase 1. | Argininosuccinate synthase 1. | 0.965 |
| CPS1 | CAD | ENSAMEP00000005446 | ENSAMEP00000001870 | Carbamoyl-phosphate synthase 1. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.902 |
| CPS1 | DHODH | ENSAMEP00000005446 | ENSAMEP00000002674 | Carbamoyl-phosphate synthase 1. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.820 |
| CPS1 | GART | ENSAMEP00000005446 | ENSAMEP00000015701 | Carbamoyl-phosphate synthase 1. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.836 |