RASGEF1B protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RASGEF1B

RasGEF domain family member 1B. (472 aa)

Predicted Functional Partners:

HAUS8

0.730

SLC26A3

0.690

ARHGAP5

0.632

ARHGAP12

0.616

LINGO1

0.606

KCTD7

0.604

ARFGEF3

0.541

PHACTR2

0.532

EPB41L4B

0.528

PPP2R2C

0.518

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARFGEF3	PHACTR2	ENSAMEP00000012495	ENSAMEP00000012162	ARFGEF family member 3.	Phosphatase and actin regulator.	0.612
ARFGEF3	RASGEF1B	ENSAMEP00000012495	ENSAMEP00000005487	ARFGEF family member 3.	RasGEF domain family member 1B.	0.541
ARHGAP12	ARHGAP5	ENSAMEP00000010811	ENSAMEP00000016572	Rho GTPase activating protein 12.	Rho GTPase activating protein 5.	0.519
ARHGAP12	HAUS8	ENSAMEP00000010811	ENSAMEP00000010749	Rho GTPase activating protein 12.	HAUS augmin like complex subunit 8.	0.725
ARHGAP12	KCTD7	ENSAMEP00000010811	ENSAMEP00000019213	Rho GTPase activating protein 12.	Uncharacterized protein.	0.618
ARHGAP12	RASGEF1B	ENSAMEP00000010811	ENSAMEP00000005487	Rho GTPase activating protein 12.	RasGEF domain family member 1B.	0.616
ARHGAP5	ARHGAP12	ENSAMEP00000016572	ENSAMEP00000010811	Rho GTPase activating protein 5.	Rho GTPase activating protein 12.	0.519
ARHGAP5	HAUS8	ENSAMEP00000016572	ENSAMEP00000010749	Rho GTPase activating protein 5.	HAUS augmin like complex subunit 8.	0.750
ARHGAP5	KCTD7	ENSAMEP00000016572	ENSAMEP00000019213	Rho GTPase activating protein 5.	Uncharacterized protein.	0.631
ARHGAP5	RASGEF1B	ENSAMEP00000016572	ENSAMEP00000005487	Rho GTPase activating protein 5.	RasGEF domain family member 1B.	0.632
EPB41L4B	RASGEF1B	ENSAMEP00000019089	ENSAMEP00000005487	Erythrocyte membrane protein band 4.1 like 4B.	RasGEF domain family member 1B.	0.528
HAUS8	ARHGAP12	ENSAMEP00000010749	ENSAMEP00000010811	HAUS augmin like complex subunit 8.	Rho GTPase activating protein 12.	0.725
HAUS8	ARHGAP5	ENSAMEP00000010749	ENSAMEP00000016572	HAUS augmin like complex subunit 8.	Rho GTPase activating protein 5.	0.750
HAUS8	KCTD7	ENSAMEP00000010749	ENSAMEP00000019213	HAUS augmin like complex subunit 8.	Uncharacterized protein.	0.759
HAUS8	RASGEF1B	ENSAMEP00000010749	ENSAMEP00000005487	HAUS augmin like complex subunit 8.	RasGEF domain family member 1B.	0.730
KCTD7	ARHGAP12	ENSAMEP00000019213	ENSAMEP00000010811	Uncharacterized protein.	Rho GTPase activating protein 12.	0.618
KCTD7	ARHGAP5	ENSAMEP00000019213	ENSAMEP00000016572	Uncharacterized protein.	Rho GTPase activating protein 5.	0.631
KCTD7	HAUS8	ENSAMEP00000019213	ENSAMEP00000010749	Uncharacterized protein.	HAUS augmin like complex subunit 8.	0.759
KCTD7	RASGEF1B	ENSAMEP00000019213	ENSAMEP00000005487	Uncharacterized protein.	RasGEF domain family member 1B.	0.604
LINGO1	RASGEF1B	ENSAMEP00000020330	ENSAMEP00000005487	Leucine rich repeat and Ig domain containing 1.	RasGEF domain family member 1B.	0.606