HMGXB3 protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HMGXB3

HMG-box containing 3. (1247 aa)

Predicted Functional Partners:

SLC26A2

0.603

NRSN2

0.603

ERI1

0.540

SASS6

0.532

EDC4

0.504

TARBP2

0.491

MYADM

0.449

LYPLAL1

0.444

G1MBP0_AILME

0.442

MFSD14A

0.438

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDC4	ERI1	ENSAMEP00000018559	ENSAMEP00000016903	Enhancer of mRNA decapping 4.	Exoribonuclease 1.	0.457
EDC4	HMGXB3	ENSAMEP00000018559	ENSAMEP00000005495	Enhancer of mRNA decapping 4.	HMG-box containing 3.	0.504
ERI1	EDC4	ENSAMEP00000016903	ENSAMEP00000018559	Exoribonuclease 1.	Enhancer of mRNA decapping 4.	0.457
ERI1	HMGXB3	ENSAMEP00000016903	ENSAMEP00000005495	Exoribonuclease 1.	HMG-box containing 3.	0.540
G1MBP0_AILME	HMGXB3	ENSAMEP00000016768	ENSAMEP00000005495	Uncharacterized protein.	HMG-box containing 3.	0.442
HMGXB3	EDC4	ENSAMEP00000005495	ENSAMEP00000018559	HMG-box containing 3.	Enhancer of mRNA decapping 4.	0.504
HMGXB3	ERI1	ENSAMEP00000005495	ENSAMEP00000016903	HMG-box containing 3.	Exoribonuclease 1.	0.540
HMGXB3	G1MBP0_AILME	ENSAMEP00000005495	ENSAMEP00000016768	HMG-box containing 3.	Uncharacterized protein.	0.442
HMGXB3	LYPLAL1	ENSAMEP00000005495	ENSAMEP00000011426	HMG-box containing 3.	Lysophospholipase like 1.	0.444
HMGXB3	MFSD14A	ENSAMEP00000005495	ENSAMEP00000009481	HMG-box containing 3.	MFS domain-containing protein.	0.438
HMGXB3	MYADM	ENSAMEP00000005495	ENSAMEP00000020423	HMG-box containing 3.	Myeloid associated differentiation marker.	0.449
HMGXB3	NRSN2	ENSAMEP00000005495	ENSAMEP00000014756	HMG-box containing 3.	Neurensin 2.	0.603
HMGXB3	SASS6	ENSAMEP00000005495	ENSAMEP00000009434	HMG-box containing 3.	SAS-6 centriolar assembly protein.	0.532
HMGXB3	SLC26A2	ENSAMEP00000005495	ENSAMEP00000005503	HMG-box containing 3.	Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	0.603
HMGXB3	TARBP2	ENSAMEP00000005495	ENSAMEP00000013275	HMG-box containing 3.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.491
LYPLAL1	HMGXB3	ENSAMEP00000011426	ENSAMEP00000005495	Lysophospholipase like 1.	HMG-box containing 3.	0.444
LYPLAL1	NRSN2	ENSAMEP00000011426	ENSAMEP00000014756	Lysophospholipase like 1.	Neurensin 2.	0.569
MFSD14A	HMGXB3	ENSAMEP00000009481	ENSAMEP00000005495	MFS domain-containing protein.	HMG-box containing 3.	0.438
MFSD14A	SASS6	ENSAMEP00000009481	ENSAMEP00000009434	MFS domain-containing protein.	SAS-6 centriolar assembly protein.	0.435
MYADM	HMGXB3	ENSAMEP00000020423	ENSAMEP00000005495	Myeloid associated differentiation marker.	HMG-box containing 3.	0.449