SMO protein (Ailuropoda melanoleuca) - STRING interaction network

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[Homology]

Score

SMO

Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (767 aa)

Predicted Functional Partners:

PTCH1

0.994

PTCH2

0.988

SUFU

0.987

PRKACA

0.977

PRKACB

0.970

GRK2

0.960

GRK3

0.960

EVC2

0.945

BOC

0.942

MOSMO

0.939

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOC	PTCH1	ENSAMEP00000019104	ENSAMEP00000012253	BOC cell adhesion associated, oncogene regulated.	Patched 1.	0.964
BOC	PTCH2	ENSAMEP00000019104	ENSAMEP00000015007	BOC cell adhesion associated, oncogene regulated.	Patched 2.	0.954
BOC	SMO	ENSAMEP00000019104	ENSAMEP00000005502	BOC cell adhesion associated, oncogene regulated.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.942
EVC2	GRK2	ENSAMEP00000011739	ENSAMEP00000000692	EvC ciliary complex subunit 2.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.538
EVC2	GRK3	ENSAMEP00000011739	ENSAMEP00000018994	EvC ciliary complex subunit 2.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.418
EVC2	SMO	ENSAMEP00000011739	ENSAMEP00000005502	EvC ciliary complex subunit 2.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.945
EVC2	SUFU	ENSAMEP00000011739	ENSAMEP00000018813	EvC ciliary complex subunit 2.	SUFU negative regulator of hedgehog signaling.	0.609
GRK2	EVC2	ENSAMEP00000000692	ENSAMEP00000011739	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	EvC ciliary complex subunit 2.	0.538
GRK2	GRK3	ENSAMEP00000000692	ENSAMEP00000018994	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.904
GRK2	PTCH1	ENSAMEP00000000692	ENSAMEP00000012253	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Patched 1.	0.486
GRK2	SMO	ENSAMEP00000000692	ENSAMEP00000005502	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.960
GRK2	SUFU	ENSAMEP00000000692	ENSAMEP00000018813	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	SUFU negative regulator of hedgehog signaling.	0.424
GRK3	EVC2	ENSAMEP00000018994	ENSAMEP00000011739	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	EvC ciliary complex subunit 2.	0.418
GRK3	GRK2	ENSAMEP00000018994	ENSAMEP00000000692	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.904
GRK3	PTCH1	ENSAMEP00000018994	ENSAMEP00000012253	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Patched 1.	0.480
GRK3	SMO	ENSAMEP00000018994	ENSAMEP00000005502	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.960
MOSMO	SMO	ENSAMEP00000003936	ENSAMEP00000005502	Modulator of smoothened.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.939
PRKACA	PRKACB	ENSAMEP00000013901	ENSAMEP00000014254	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.953
PRKACA	SMO	ENSAMEP00000013901	ENSAMEP00000005502	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.977
PRKACA	SUFU	ENSAMEP00000013901	ENSAMEP00000018813	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	SUFU negative regulator of hedgehog signaling.	0.848