STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCPH1BRCT domain-containing protein. (663 aa)    
Predicted Functional Partners:
SLF1
SMC5-SMC6 complex localization factor 1.
   
 0.818
G1L0X7_AILME
Uncharacterized protein.
   
 0.784
WRN
3'-5' exonuclease domain-containing protein.
   
 0.784
TOPBP1
DNA topoisomerase II binding protein 1.
   
 0.783
ASPM
Abnormal spindle microtubule assembly.
   
  
 0.770
REL
REL proto-oncogene, NF-kB subunit.
    
 0.764
WDR62
WD repeat domain 62.
   
  
 0.749
HOXD13
Homeobox D13.
      
 0.746
BRCA2
BRCA2 DNA repair associated.
   
 0.735
APEX2
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
      
 0.727
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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