STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)    
Predicted Functional Partners:
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.999
CCND1
Cyclin D1; Belongs to the cyclin family.
   
 0.999
CCND3
Cyclin D3; Belongs to the cyclin family.
   
 0.999
CCND2
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.999
RB1
RB transcriptional corepressor 1.
   
 0.997
CDKN2C
Cyclin dependent kinase inhibitor 2C.
   
 0.997
CCNE1
Cyclin E1; Belongs to the cyclin family.
   
 0.995
CDKN2B
Cyclin dependent kinase inhibitor 2B.
    
 0.994
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.994
CCNA2
Cyclin A2; Belongs to the cyclin family.
 
 
 0.993
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.