TLE2 protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Gene Fusion

Cooccurrence

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Experiments

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[Homology]

Score

TLE2

TLE family member 2, transcriptional corepressor. (759 aa)

Predicted Functional Partners:

NRIP1

0.813

FOXA1

0.764

EP300

0.757

GATA3

0.735

LEF1

0.586

TCF7L1

0.586

TCF7L2

0.586

TCF7

0.586

TLE1

0.523

HES1

0.503

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EP300	FOXA1	ENSAMEP00000014751	ENSAMEP00000008423	E1A binding protein p300.	Forkhead box A1.	0.926
EP300	GATA3	ENSAMEP00000014751	ENSAMEP00000013596	E1A binding protein p300.	GATA binding protein 3.	0.937
EP300	LEF1	ENSAMEP00000014751	ENSAMEP00000001900	E1A binding protein p300.	Lymphoid enhancer binding factor 1.	0.967
EP300	NRIP1	ENSAMEP00000014751	ENSAMEP00000019809	E1A binding protein p300.	Nuclear receptor interacting protein 1.	0.924
EP300	TCF7	ENSAMEP00000014751	ENSAMEP00000018808	E1A binding protein p300.	Transcription factor 7.	0.672
EP300	TCF7L1	ENSAMEP00000014751	ENSAMEP00000002181	E1A binding protein p300.	Transcription factor 7 like 1.	0.959
EP300	TCF7L2	ENSAMEP00000014751	ENSAMEP00000016224	E1A binding protein p300.	Transcription factor 7 like 2.	0.633
EP300	TLE1	ENSAMEP00000014751	ENSAMEP00000015373	E1A binding protein p300.	TLE family member 1, transcriptional corepressor.	0.530
EP300	TLE2	ENSAMEP00000014751	ENSAMEP00000005753	E1A binding protein p300.	TLE family member 2, transcriptional corepressor.	0.757
FOXA1	EP300	ENSAMEP00000008423	ENSAMEP00000014751	Forkhead box A1.	E1A binding protein p300.	0.926
FOXA1	GATA3	ENSAMEP00000008423	ENSAMEP00000013596	Forkhead box A1.	GATA binding protein 3.	0.978
FOXA1	NRIP1	ENSAMEP00000008423	ENSAMEP00000019809	Forkhead box A1.	Nuclear receptor interacting protein 1.	0.923
FOXA1	TLE1	ENSAMEP00000008423	ENSAMEP00000015373	Forkhead box A1.	TLE family member 1, transcriptional corepressor.	0.460
FOXA1	TLE2	ENSAMEP00000008423	ENSAMEP00000005753	Forkhead box A1.	TLE family member 2, transcriptional corepressor.	0.764
GATA3	EP300	ENSAMEP00000013596	ENSAMEP00000014751	GATA binding protein 3.	E1A binding protein p300.	0.937
GATA3	FOXA1	ENSAMEP00000013596	ENSAMEP00000008423	GATA binding protein 3.	Forkhead box A1.	0.978
GATA3	LEF1	ENSAMEP00000013596	ENSAMEP00000001900	GATA binding protein 3.	Lymphoid enhancer binding factor 1.	0.513
GATA3	NRIP1	ENSAMEP00000013596	ENSAMEP00000019809	GATA binding protein 3.	Nuclear receptor interacting protein 1.	0.917
GATA3	TCF7	ENSAMEP00000013596	ENSAMEP00000018808	GATA binding protein 3.	Transcription factor 7.	0.436
GATA3	TCF7L2	ENSAMEP00000013596	ENSAMEP00000016224	GATA binding protein 3.	Transcription factor 7 like 2.	0.450