STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITKTyrosine-protein kinase. (620 aa)    
Predicted Functional Partners:
LCP2
Lymphocyte cytosolic protein 2.
   
 0.989
PLCG1
Phosphoinositide phospholipase C.
   
0.973
VAV1
Uncharacterized protein.
   
 0.972
TXK
Tyrosine-protein kinase.
  
 
 
0.958
VAV2
Vav guanine nucleotide exchange factor 2.
   
 0.958
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.957
HCK
Tyrosine-protein kinase.
  
0.957
TEC
Tyrosine-protein kinase.
  
  
 
0.946
LYN
Tyrosine-protein kinase.
  
0.940
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.929
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.