| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DCN | EGF | ENSAMEP00000004619 | ENSAMEP00000015773 | Decorin; May affect the rate of fibrils formation. | Epidermal growth factor. | 0.461 |
| DCN | HGF | ENSAMEP00000004619 | ENSAMEP00000017509 | Decorin; May affect the rate of fibrils formation. | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.438 |
| DCN | IGF1 | ENSAMEP00000004619 | ENSAMEP00000006724 | Decorin; May affect the rate of fibrils formation. | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] | 0.943 |
| EGF | DCN | ENSAMEP00000015773 | ENSAMEP00000004619 | Epidermal growth factor. | Decorin; May affect the rate of fibrils formation. | 0.461 |
| EGF | HGF | ENSAMEP00000015773 | ENSAMEP00000017509 | Epidermal growth factor. | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.968 |
| EGF | IGF1 | ENSAMEP00000015773 | ENSAMEP00000006724 | Epidermal growth factor. | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] | 0.961 |
| EGF | IGF1R | ENSAMEP00000015773 | ENSAMEP00000006007 | Epidermal growth factor. | Tyrosine-protein kinase receptor. | 0.909 |
| EGF | INS-IGF2 | ENSAMEP00000015773 | ENSAMEP00000002279 | Epidermal growth factor. | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.983 |
| EGF | INSR | ENSAMEP00000015773 | ENSAMEP00000008683 | Epidermal growth factor. | Tyrosine-protein kinase receptor. | 0.939 |
| EGF | VEGFC | ENSAMEP00000015773 | ENSAMEP00000018099 | Epidermal growth factor. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.924 |
| G1M8B3_AILME | IGF1 | ENSAMEP00000015583 | ENSAMEP00000006724 | Uncharacterized protein. | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] | 0.949 |
| G1M8B3_AILME | IGF2 | ENSAMEP00000015583 | ENSAMEP00000002277 | Uncharacterized protein. | Insulin like growth factor 2. | 0.947 |
| G1M8B3_AILME | IGFBP3 | ENSAMEP00000015583 | ENSAMEP00000015567 | Uncharacterized protein. | Thyroglobulin type-1 domain-containing protein. | 0.761 |
| G1M8B3_AILME | INS-IGF2 | ENSAMEP00000015583 | ENSAMEP00000002279 | Uncharacterized protein. | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.629 |
| HGF | DCN | ENSAMEP00000017509 | ENSAMEP00000004619 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Decorin; May affect the rate of fibrils formation. | 0.438 |
| HGF | EGF | ENSAMEP00000017509 | ENSAMEP00000015773 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Epidermal growth factor. | 0.968 |
| HGF | IGF1 | ENSAMEP00000017509 | ENSAMEP00000006724 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] | 0.951 |
| HGF | IGF1R | ENSAMEP00000017509 | ENSAMEP00000006007 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Tyrosine-protein kinase receptor. | 0.684 |
| HGF | IGF2 | ENSAMEP00000017509 | ENSAMEP00000002277 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Insulin like growth factor 2. | 0.446 |
| HGF | INS-IGF2 | ENSAMEP00000017509 | ENSAMEP00000002279 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.608 |