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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)    
Predicted Functional Partners:
IFNGR1
Interferon gamma receptor 1.
    
 0.999
IFNGR2
Interferon gamma receptor 2.
    
 0.998
JAK1
Tyrosine-protein kinase.
   
 
 0.983
JAK2
Tyrosine-protein kinase.
   
 
 0.973
CD4
Ig-like domain-containing protein.
   
  
 0.972
IFNAR1
Interferon alpha and beta receptor subunit 1.
     
 0.971
FOXP3
Forkhead box P3.
   
 0.952
IFNAR2
Uncharacterized protein.
  
 
 0.947
PSME1
Uncharacterized protein.
   
 
 0.928
IL10
Interleukin 10.
   
  
 0.921
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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