STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBX4T-box transcription factor 4. (548 aa)    
Predicted Functional Partners:
ATP7A
ATPase copper transporting alpha.
   
  
 0.729
BDNF
Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]
      
 0.724
NKX2-5
NK2 homeobox 5.
   
 
 0.688
HOXC10
Homeobox C10.
    
 
 0.628
SOX2
SRY-box transcription factor 2.
    
 0.625
YAP1
Yes associated protein 1.
    
 0.535
WWTR1
WW domain containing transcription regulator 1.
    
 0.535
SLC35B4
Solute carrier family 35 member B4.
      
 0.529
G1L4Y8_AILME
Homeobox domain-containing protein.
    
 
 0.526
PITX1
Homeobox protein.
   
 
 0.523
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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