TARDBP protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TARDBP

Uncharacterized protein. (414 aa)

Predicted Functional Partners:

CHCHD10

0.942

PRKN

0.926

HDAC6

0.923

PPP3CC

0.907

PPP3CA

0.907

PPP3CB

0.907

FUS

0.778

GSC

0.775

G1L799_AILME

0.759

HNRNPK

0.747

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHCHD10	FUS	ENSAMEP00000014366	ENSAMEP00000007554	Coiled-coil-helix-coiled-coil-helix domain containing 10.	FUS RNA binding protein.	0.446
CHCHD10	TARDBP	ENSAMEP00000014366	ENSAMEP00000009952	Coiled-coil-helix-coiled-coil-helix domain containing 10.	Uncharacterized protein.	0.942
FUS	CHCHD10	ENSAMEP00000007554	ENSAMEP00000014366	FUS RNA binding protein.	Coiled-coil-helix-coiled-coil-helix domain containing 10.	0.446
FUS	G1L799_AILME	ENSAMEP00000007554	ENSAMEP00000002765	FUS RNA binding protein.	Uncharacterized protein.	0.734
FUS	HNRNPK	ENSAMEP00000007554	ENSAMEP00000004170	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein K.	0.776
FUS	TARDBP	ENSAMEP00000007554	ENSAMEP00000009952	FUS RNA binding protein.	Uncharacterized protein.	0.778
G1L799_AILME	FUS	ENSAMEP00000002765	ENSAMEP00000007554	Uncharacterized protein.	FUS RNA binding protein.	0.734
G1L799_AILME	HNRNPK	ENSAMEP00000002765	ENSAMEP00000004170	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein K.	0.861
G1L799_AILME	TARDBP	ENSAMEP00000002765	ENSAMEP00000009952	Uncharacterized protein.	Uncharacterized protein.	0.759
GSC	TARDBP	ENSAMEP00000006777	ENSAMEP00000009952	Goosecoid homeobox.	Uncharacterized protein.	0.775
HDAC6	PRKN	ENSAMEP00000013236	ENSAMEP00000016749	Histone deacetylase 6.	Ubiquitin-like domain-containing protein.	0.846
HDAC6	TARDBP	ENSAMEP00000013236	ENSAMEP00000009952	Histone deacetylase 6.	Uncharacterized protein.	0.923
HNRNPK	FUS	ENSAMEP00000004170	ENSAMEP00000007554	Heterogeneous nuclear ribonucleoprotein K.	FUS RNA binding protein.	0.776
HNRNPK	G1L799_AILME	ENSAMEP00000004170	ENSAMEP00000002765	Heterogeneous nuclear ribonucleoprotein K.	Uncharacterized protein.	0.861
HNRNPK	TARDBP	ENSAMEP00000004170	ENSAMEP00000009952	Heterogeneous nuclear ribonucleoprotein K.	Uncharacterized protein.	0.747
PPP3CA	PPP3CB	ENSAMEP00000009260	ENSAMEP00000017848	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase.	0.953
PPP3CA	PPP3CC	ENSAMEP00000009260	ENSAMEP00000003306	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase.	0.910
PPP3CA	TARDBP	ENSAMEP00000009260	ENSAMEP00000009952	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.907
PPP3CB	PPP3CA	ENSAMEP00000017848	ENSAMEP00000009260	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase.	0.953
PPP3CB	PPP3CC	ENSAMEP00000017848	ENSAMEP00000003306	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase.	0.911