STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL3Cullin 3; Belongs to the cullin family. (791 aa)    
Predicted Functional Partners:
KEAP1
Kelch like ECH associated protein 1.
    
 0.999
SPOP
Speckle type BTB/POZ protein.
   
 0.998
RBX1
Ring-box 1.
    
 0.997
SPOPL
Speckle type BTB/POZ protein like.
   
 0.995
KLHL3
Kelch like family member 3.
    
 0.985
KLHL12
Kelch like family member 12.
    
 0.975
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.967
KLHL20
Kelch like family member 20.
    
 0.957
GLI3
GLI family zinc finger 3.
    
 0.956
GLI1
GLI family zinc finger 1.
    
 0.950
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.