POLH protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAD2L2	PCNA	ENSAMEP00000010248	ENSAMEP00000009571	Mitotic arrest deficient 2 like 2.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.830
MAD2L2	POLH	ENSAMEP00000010248	ENSAMEP00000012832	Mitotic arrest deficient 2 like 2.	DNA polymerase eta.	0.892
MAD2L2	POLI	ENSAMEP00000010248	ENSAMEP00000018169	Mitotic arrest deficient 2 like 2.	DNA polymerase iota.	0.859
MAD2L2	RAD18	ENSAMEP00000010248	ENSAMEP00000013038	Mitotic arrest deficient 2 like 2.	RAD18 E3 ubiquitin protein ligase.	0.570
MAD2L2	REV1	ENSAMEP00000010248	ENSAMEP00000013965	Mitotic arrest deficient 2 like 2.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.993
MAD2L2	REV3L	ENSAMEP00000010248	ENSAMEP00000011961	Mitotic arrest deficient 2 like 2.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.999
MAD2L2	RPS27A	ENSAMEP00000010248	ENSAMEP00000004241	Mitotic arrest deficient 2 like 2.	Ubiquitin-like domain-containing protein.	0.750
MAD2L2	UBB	ENSAMEP00000010248	ENSAMEP00000020185	Mitotic arrest deficient 2 like 2.	Ubiquitin B.	0.572
MAD2L2	UBE2V2	ENSAMEP00000010248	ENSAMEP00000001725	Mitotic arrest deficient 2 like 2.	Ubiquitin conjugating enzyme E2 V2.	0.663
PCNA	MAD2L2	ENSAMEP00000009571	ENSAMEP00000010248	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Mitotic arrest deficient 2 like 2.	0.830
PCNA	POLH	ENSAMEP00000009571	ENSAMEP00000012832	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase eta.	0.988
PCNA	POLI	ENSAMEP00000009571	ENSAMEP00000018169	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase iota.	0.979
PCNA	RAD18	ENSAMEP00000009571	ENSAMEP00000013038	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	RAD18 E3 ubiquitin protein ligase.	0.991
PCNA	RCHY1	ENSAMEP00000009571	ENSAMEP00000015166	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ring finger and CHY zinc finger domain containing 1.	0.535
PCNA	REV1	ENSAMEP00000009571	ENSAMEP00000013965	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.965
PCNA	REV3L	ENSAMEP00000009571	ENSAMEP00000011961	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.937
PCNA	RPS27A	ENSAMEP00000009571	ENSAMEP00000004241	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin-like domain-containing protein.	0.946
PCNA	UBB	ENSAMEP00000009571	ENSAMEP00000020185	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin B.	0.885
PCNA	UBE2V2	ENSAMEP00000009571	ENSAMEP00000001725	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin conjugating enzyme E2 V2.	0.943
POLH	MAD2L2	ENSAMEP00000012832	ENSAMEP00000010248	DNA polymerase eta.	Mitotic arrest deficient 2 like 2.	0.892