node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYP7A1 | NR1H4 | ENSAMEP00000006480 | ENSAMEP00000016082 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | Nuclear receptor subfamily 1 group H member 4. | 0.752 |
MED1 | NCOA1 | ENSAMEP00000004219 | ENSAMEP00000002847 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.647 |
MED1 | NCOA2 | ENSAMEP00000004219 | ENSAMEP00000006644 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.555 |
MED1 | NCOR1 | ENSAMEP00000004219 | ENSAMEP00000004955 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 1. | 0.533 |
MED1 | NCOR2 | ENSAMEP00000004219 | ENSAMEP00000016359 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 2. | 0.563 |
MED1 | NR1H4 | ENSAMEP00000004219 | ENSAMEP00000016082 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 4. | 0.741 |
MED1 | RXRA | ENSAMEP00000004219 | ENSAMEP00000011750 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor alpha. | 0.916 |
MED1 | RXRB | ENSAMEP00000004219 | ENSAMEP00000001817 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor beta. | 0.907 |
MED1 | RXRG | ENSAMEP00000004219 | ENSAMEP00000006999 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor gamma. | 0.916 |
NCOA1 | MED1 | ENSAMEP00000002847 | ENSAMEP00000004219 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.647 |
NCOA1 | NCOA2 | ENSAMEP00000002847 | ENSAMEP00000006644 | Nuclear receptor coactivator. | Nuclear receptor coactivator. | 0.996 |
NCOA1 | NCOR1 | ENSAMEP00000002847 | ENSAMEP00000004955 | Nuclear receptor coactivator. | Nuclear receptor corepressor 1. | 0.661 |
NCOA1 | NCOR2 | ENSAMEP00000002847 | ENSAMEP00000016359 | Nuclear receptor coactivator. | Nuclear receptor corepressor 2. | 0.647 |
NCOA1 | NR1H4 | ENSAMEP00000002847 | ENSAMEP00000016082 | Nuclear receptor coactivator. | Nuclear receptor subfamily 1 group H member 4. | 0.908 |
NCOA1 | PPARGC1A | ENSAMEP00000002847 | ENSAMEP00000011007 | Nuclear receptor coactivator. | PPARG coactivator 1 alpha. | 0.485 |
NCOA1 | RXRA | ENSAMEP00000002847 | ENSAMEP00000011750 | Nuclear receptor coactivator. | Retinoid X receptor alpha. | 0.979 |
NCOA1 | RXRB | ENSAMEP00000002847 | ENSAMEP00000001817 | Nuclear receptor coactivator. | Retinoid X receptor beta. | 0.892 |
NCOA1 | RXRG | ENSAMEP00000002847 | ENSAMEP00000006999 | Nuclear receptor coactivator. | Retinoid X receptor gamma. | 0.937 |
NCOA2 | MED1 | ENSAMEP00000006644 | ENSAMEP00000004219 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.555 |
NCOA2 | NCOA1 | ENSAMEP00000006644 | ENSAMEP00000002847 | Nuclear receptor coactivator. | Nuclear receptor coactivator. | 0.996 |