STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBM25RNA binding motif protein 25. (843 aa)    
Predicted Functional Partners:
LUC7L3
LUC7 like 3 pre-mRNA splicing factor.
   
 0.987
SART1
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
   
 
 0.974
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
   
 
 0.973
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
   
 
 0.967
RBM39
RNA binding motif protein 39.
   
0.955
PRPF40A
Pre-mRNA processing factor 40 homolog A.
   
 0.955
SF3B3
Splicing factor 3b subunit 3.
    
 
 0.953
U2AF2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 
 0.953
SRRM1
Serine and arginine repetitive matrix 1.
   
 0.951
PRPF40B
Pre-mRNA processing factor 40 homolog B.
   
 
 0.950
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.