IRF1 protein (Ailuropoda melanoleuca) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

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Score

IRF1

Interferon regulatory factor 1. (322 aa)

Predicted Functional Partners:

STAT1

0.946

HDAC1

0.942

HDAC2

0.942

MDM2

0.930

CHD4

0.908

IRF8

0.766

STAT2

0.728

ISG15

0.721

STAT3

0.704

CD4

0.696

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	HDAC1	ENSAMEP00000014814	ENSAMEP00000008076	Ig-like domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.449
CD4	HDAC2	ENSAMEP00000014814	ENSAMEP00000013919	Ig-like domain-containing protein.	Histone deacetylase 2.	0.449
CD4	IRF1	ENSAMEP00000014814	ENSAMEP00000018700	Ig-like domain-containing protein.	Interferon regulatory factor 1.	0.696
CD4	IRF8	ENSAMEP00000014814	ENSAMEP00000019310	Ig-like domain-containing protein.	Interferon regulatory factor 8.	0.639
CD4	ISG15	ENSAMEP00000014814	ENSAMEP00000019594	Ig-like domain-containing protein.	ISG15 ubiquitin like modifier.	0.595
CD4	STAT1	ENSAMEP00000014814	ENSAMEP00000014970	Ig-like domain-containing protein.	Signal transducer and activator of transcription.	0.790
CD4	STAT2	ENSAMEP00000014814	ENSAMEP00000004145	Ig-like domain-containing protein.	Signal transducer and activator of transcription.	0.502
CD4	STAT3	ENSAMEP00000014814	ENSAMEP00000006689	Ig-like domain-containing protein.	Signal transducer and activator of transcription.	0.919
CHD4	HDAC1	ENSAMEP00000015028	ENSAMEP00000008076	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.969
CHD4	HDAC2	ENSAMEP00000015028	ENSAMEP00000013919	Uncharacterized protein.	Histone deacetylase 2.	0.969
CHD4	IRF1	ENSAMEP00000015028	ENSAMEP00000018700	Uncharacterized protein.	Interferon regulatory factor 1.	0.908
HDAC1	CD4	ENSAMEP00000008076	ENSAMEP00000014814	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Ig-like domain-containing protein.	0.449
HDAC1	CHD4	ENSAMEP00000008076	ENSAMEP00000015028	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Uncharacterized protein.	0.969
HDAC1	HDAC2	ENSAMEP00000008076	ENSAMEP00000013919	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.993
HDAC1	IRF1	ENSAMEP00000008076	ENSAMEP00000018700	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Interferon regulatory factor 1.	0.942
HDAC1	MDM2	ENSAMEP00000008076	ENSAMEP00000009001	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.456
HDAC1	STAT1	ENSAMEP00000008076	ENSAMEP00000014970	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Signal transducer and activator of transcription.	0.632
HDAC1	STAT2	ENSAMEP00000008076	ENSAMEP00000004145	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Signal transducer and activator of transcription.	0.489
HDAC1	STAT3	ENSAMEP00000008076	ENSAMEP00000006689	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Signal transducer and activator of transcription.	0.586
HDAC2	CD4	ENSAMEP00000013919	ENSAMEP00000014814	Histone deacetylase 2.	Ig-like domain-containing protein.	0.449