CHRM2 protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRM2	GNA14	ENSAMEP00000020788	ENSAMEP00000005586	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha 14.	0.914
CHRM2	GNA15	ENSAMEP00000020788	ENSAMEP00000005791	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha 15.	0.912
CHRM2	GNAO1	ENSAMEP00000020788	ENSAMEP00000017539	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha o1.	0.924
CHRM2	GNB2	ENSAMEP00000020788	ENSAMEP00000015571	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit beta 2.	0.930
CHRM2	GNB3	ENSAMEP00000020788	ENSAMEP00000014773	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit beta 3.	0.917
CHRM2	GNB5	ENSAMEP00000020788	ENSAMEP00000007574	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit beta 5.	0.930
CHRM2	GNG11	ENSAMEP00000020788	ENSAMEP00000018737	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.912
CHRM2	GNG4	ENSAMEP00000020788	ENSAMEP00000003254	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.942
CHRM2	LPAR3	ENSAMEP00000020788	ENSAMEP00000018274	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.916
CHRM2	SST	ENSAMEP00000020788	ENSAMEP00000000865	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Somatostatin.	0.915
GNA14	CHRM2	ENSAMEP00000005586	ENSAMEP00000020788	G protein subunit alpha 14.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.914
GNA14	GNA15	ENSAMEP00000005586	ENSAMEP00000005791	G protein subunit alpha 14.	G protein subunit alpha 15.	0.904
GNA14	GNAO1	ENSAMEP00000005586	ENSAMEP00000017539	G protein subunit alpha 14.	G protein subunit alpha o1.	0.898
GNA14	GNB2	ENSAMEP00000005586	ENSAMEP00000015571	G protein subunit alpha 14.	G protein subunit beta 2.	0.873
GNA14	GNB3	ENSAMEP00000005586	ENSAMEP00000014773	G protein subunit alpha 14.	G protein subunit beta 3.	0.849
GNA14	GNB5	ENSAMEP00000005586	ENSAMEP00000007574	G protein subunit alpha 14.	G protein subunit beta 5.	0.864
GNA14	GNG11	ENSAMEP00000005586	ENSAMEP00000018737	G protein subunit alpha 14.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.715
GNA14	GNG4	ENSAMEP00000005586	ENSAMEP00000003254	G protein subunit alpha 14.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.920
GNA14	LPAR3	ENSAMEP00000005586	ENSAMEP00000018274	G protein subunit alpha 14.	Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.754
GNA15	CHRM2	ENSAMEP00000005791	ENSAMEP00000020788	G protein subunit alpha 15.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.912