SORT1 protein (Ailuropoda melanoleuca) - STRING interaction network

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Predicted Interactions

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Score

SORT1

Sortilin. (814 aa)

Predicted Functional Partners:

NTS

0.958

APOB

0.934

NGFR

0.916

BDNF

0.855

NGF

0.815

GRN

0.779

PSAP

0.769

GAK

0.766

GGA2

0.762

IGF2R

0.741

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOB	BDNF	ENSAMEP00000013815	ENSAMEP00000015321	Vitellogenin domain-containing protein.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.503
APOB	SORT1	ENSAMEP00000013815	ENSAMEP00000005013	Vitellogenin domain-containing protein.	Sortilin.	0.934
BDNF	APOB	ENSAMEP00000015321	ENSAMEP00000013815	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Vitellogenin domain-containing protein.	0.503
BDNF	NGF	ENSAMEP00000015321	ENSAMEP00000019842	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Nerve growth factor; Belongs to the NGF-beta family.	0.792
BDNF	NGFR	ENSAMEP00000015321	ENSAMEP00000013005	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Nerve growth factor receptor.	0.914
BDNF	SORT1	ENSAMEP00000015321	ENSAMEP00000005013	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Sortilin.	0.855
GAK	IGF2R	ENSAMEP00000017732	ENSAMEP00000016198	Cyclin G associated kinase.	Insulin like growth factor 2 receptor.	0.923
GAK	SORT1	ENSAMEP00000017732	ENSAMEP00000005013	Cyclin G associated kinase.	Sortilin.	0.766
GGA2	IGF2R	ENSAMEP00000012070	ENSAMEP00000016198	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	Insulin like growth factor 2 receptor.	0.758
GGA2	SORT1	ENSAMEP00000012070	ENSAMEP00000005013	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	Sortilin.	0.762
GRN	PSAP	ENSAMEP00000019401	ENSAMEP00000018637	Granulin precursor.	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	0.641
GRN	SORT1	ENSAMEP00000019401	ENSAMEP00000005013	Granulin precursor.	Sortilin.	0.779
IGF2R	GAK	ENSAMEP00000016198	ENSAMEP00000017732	Insulin like growth factor 2 receptor.	Cyclin G associated kinase.	0.923
IGF2R	GGA2	ENSAMEP00000016198	ENSAMEP00000012070	Insulin like growth factor 2 receptor.	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	0.758
IGF2R	SORT1	ENSAMEP00000016198	ENSAMEP00000005013	Insulin like growth factor 2 receptor.	Sortilin.	0.741
NGF	BDNF	ENSAMEP00000019842	ENSAMEP00000015321	Nerve growth factor; Belongs to the NGF-beta family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.792
NGF	NGFR	ENSAMEP00000019842	ENSAMEP00000013005	Nerve growth factor; Belongs to the NGF-beta family.	Nerve growth factor receptor.	0.926
NGF	SORT1	ENSAMEP00000019842	ENSAMEP00000005013	Nerve growth factor; Belongs to the NGF-beta family.	Sortilin.	0.815
NGFR	BDNF	ENSAMEP00000013005	ENSAMEP00000015321	Nerve growth factor receptor.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.914
NGFR	NGF	ENSAMEP00000013005	ENSAMEP00000019842	Nerve growth factor receptor.	Nerve growth factor; Belongs to the NGF-beta family.	0.926