STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dole_0773KEGG: pca:Pcar_1006 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (406 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.979
Dole_0959
PFAM: aspartate/glutamate/uridylate kinase; KEGG: noc:Noc_1029 aspartate kinase.
     
  0.900
Dole_0291
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: gme:Gmet_1629 homoserine dehydrogenase.
 
 0.879
Dole_1107
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: rca:Rcas_2336 asparagine synthase (glutamine-hydrolyzing).
  
 
 0.854
Dole_1462
KEGG: ppd:Ppro_2466 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase.
  
 
 0.854
argG
PFAM: argininosuccinate synthase; KEGG: sfu:Sfum_0061 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.844
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.839
Dole_0081
PFAM: aminotransferase class I and II; KEGG: dps:DP2938 probable aspartate aminotransferase.
  
 0.837
Dole_1490
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.813
pyrB
KEGG: sfu:Sfum_2090 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
 0.808
Your Current Organism:
Desulfococcus oleovorans
NCBI taxonomy Id: 96561
Other names: D. oleovorans Hxd3, Desulfobacteirum oleovorans Hxd3, Desulfococcus oleovorans Hxd3, delta proteobacterium Hxd3, sulfate-reducing bacterium Hxd3
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.