node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dole_0071 | ubiE | Dole_0071 | Dole_1491 | PFAM: NADPH-dependent FMN reductase; flavodoxin/nitric oxide synthase; KEGG: sat:SYN_00084 multimeric flavodoxin. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
Dole_1493 | Dole_1494 | Dole_1493 | Dole_1494 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mac:MA0956 6-pyruvoyltetrahydropterin synthase. | PFAM: beta-lactamase domain protein; KEGG: swo:Swol_1480 Zn-dependent hydrolases including glyoxylases-like protein. | 0.781 |
Dole_1493 | dnaJ | Dole_1493 | Dole_1492 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mac:MA0956 6-pyruvoyltetrahydropterin synthase. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.697 |
Dole_1493 | pyrD | Dole_1493 | Dole_1495 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mac:MA0956 6-pyruvoyltetrahydropterin synthase. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.788 |
Dole_1493 | ubiE | Dole_1493 | Dole_1491 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mac:MA0956 6-pyruvoyltetrahydropterin synthase. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.472 |
Dole_1494 | Dole_1493 | Dole_1494 | Dole_1493 | PFAM: beta-lactamase domain protein; KEGG: swo:Swol_1480 Zn-dependent hydrolases including glyoxylases-like protein. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mac:MA0956 6-pyruvoyltetrahydropterin synthase. | 0.781 |
Dole_1494 | dnaJ | Dole_1494 | Dole_1492 | PFAM: beta-lactamase domain protein; KEGG: swo:Swol_1480 Zn-dependent hydrolases including glyoxylases-like protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.616 |
Dole_1494 | pyrD | Dole_1494 | Dole_1495 | PFAM: beta-lactamase domain protein; KEGG: swo:Swol_1480 Zn-dependent hydrolases including glyoxylases-like protein. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.793 |
Dole_1494 | ubiE | Dole_1494 | Dole_1491 | PFAM: beta-lactamase domain protein; KEGG: swo:Swol_1480 Zn-dependent hydrolases including glyoxylases-like protein. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.435 |
Dole_3212 | ubiE | Dole_3212 | Dole_1491 | TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: sfu:Sfum_0287 UbiD family decarboxylases; Belongs to the UbiD family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.802 |
Dole_3230 | ubiE | Dole_3230 | Dole_1491 | PFAM: Polyprenyl synthetase; KEGG: sfu:Sfum_1586 trans-hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.525 |
bioB | ubiE | Dole_0682 | Dole_1491 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.416 |
dnaJ | Dole_1493 | Dole_1492 | Dole_1493 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mac:MA0956 6-pyruvoyltetrahydropterin synthase. | 0.697 |
dnaJ | Dole_1494 | Dole_1492 | Dole_1494 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | PFAM: beta-lactamase domain protein; KEGG: swo:Swol_1480 Zn-dependent hydrolases including glyoxylases-like protein. | 0.616 |
dnaJ | pyrD | Dole_1492 | Dole_1495 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.605 |
dnaJ | ubiE | Dole_1492 | Dole_1491 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.594 |
pyrD | Dole_1493 | Dole_1495 | Dole_1493 | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mac:MA0956 6-pyruvoyltetrahydropterin synthase. | 0.788 |
pyrD | Dole_1494 | Dole_1495 | Dole_1494 | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | PFAM: beta-lactamase domain protein; KEGG: swo:Swol_1480 Zn-dependent hydrolases including glyoxylases-like protein. | 0.793 |
pyrD | dnaJ | Dole_1495 | Dole_1492 | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.605 |
pyrD | ubiE | Dole_1495 | Dole_1491 | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.455 |