Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Dole_20113-beta hydroxysteroid dehydrogenase/isomerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: gur:Gura_2007 3-beta hydroxysteroid dehydrogenase/isomerase. (330 aa)    
Predicted Functional Partners:
Dole_2010
PFAM: AMP-dependent synthetase and ligase; KEGG: gur:Gura_2008 AMP-dependent synthetase and ligase.
 
 
 0.959
Dole_2009
PFAM: alpha/beta hydrolase fold; KEGG: cps:CPS_2154 hydrolase, alpha/beta hydrolase fold family.
 
  
 0.929
Dole_2008
PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: gur:Gura_2010 3-oxoacyl-(acyl-carrier-protein (ACP)) synthase III C terminal domain protein.
 
   
 0.926
Dole_1676
TIGRFAM: Polyketide-type polyunsaturated fatty acid synthase, PfaA; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sde:Sde_0688 polyketide synthase modules and related proteins-like.
 
 
 0.787
Dole_1677
PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; Beta-ketoacyl synthase; KEGG: gur:Gura_2011 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.745
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
 0.594
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.593
rpsC
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
  0.588
rpsQ
Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.586
rpsZ
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
   
  0.584
Your Current Organism:
Desulfococcus oleovorans
NCBI taxonomy Id: 96561
Other names: D. oleovorans Hxd3, Desulfobacteirum oleovorans Hxd3, Desulfococcus oleovorans Hxd3, delta proteobacterium Hxd3, sulfate-reducing bacterium Hxd3
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