Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Dole_3205PFAM: PSP1 domain protein; KEGG: pth:PTH_0064 uncharacterized homolog of PSP1. (284 aa)    
Predicted Functional Partners:
rny
RNA binding metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
 
  
 0.863
Dole_3206
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: gsu:GSU2230 DNA polymerase III, delta prime subunit.
  
   0.839
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
       0.783
Dole_3207
PFAM: histone family protein DNA-binding protein; KEGG: pca:Pcar_1455 integration host factor, beta subunit; Belongs to the bacterial histone-like protein family.
       0.757
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.559
pyrK
Oxidoreductase FAD/NAD(P)-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
  
 0.537
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
       0.489
Dole_3201
Glutamine--fructose-6-phosphate transaminase (isomerizing); PFAM: sugar isomerase (SIS); KEGG: sat:SYN_02923 glucosamine--fructose-6-phosphate aminotransferase (isomerizing).
       0.456
Dole_3203
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: slo:Shew_1858 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.
       0.451
Dole_3202
PFAM: iron-containing alcohol dehydrogenase; KEGG: sat:SYN_00021 alcohol dehydrogenase, class IV.
       0.432
Your Current Organism:
Desulfococcus oleovorans
NCBI taxonomy Id: 96561
Other names: D. oleovorans Hxd3, Desulfobacteirum oleovorans Hxd3, Desulfococcus oleovorans Hxd3, delta proteobacterium Hxd3, sulfate-reducing bacterium Hxd3
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