| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dole_1031 | Dole_2857 | Dole_1031 | Dole_2857 | Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.879 |
| Dole_1031 | Dole_2990 | Dole_1031 | Dole_2990 | Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | TIGRFAM: CRISPR-associated protein Cas2; KEGG: csa:Csal_0233 CRISPR-associated protein, Cas2. | 0.692 |
| Dole_1031 | Dole_3207 | Dole_1031 | Dole_3207 | Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | PFAM: histone family protein DNA-binding protein; KEGG: pca:Pcar_1455 integration host factor, beta subunit; Belongs to the bacterial histone-like protein family. | 0.983 |
| Dole_1031 | cas1 | Dole_1031 | Dole_2989 | Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.811 |
| Dole_1031 | rpsT | Dole_1031 | Dole_2436 | Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.543 |
| Dole_1031 | topA | Dole_1031 | Dole_2445 | Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.588 |
| Dole_2857 | Dole_1031 | Dole_2857 | Dole_1031 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.879 |
| Dole_2857 | Dole_3207 | Dole_2857 | Dole_3207 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | PFAM: histone family protein DNA-binding protein; KEGG: pca:Pcar_1455 integration host factor, beta subunit; Belongs to the bacterial histone-like protein family. | 0.823 |
| Dole_2857 | cas1 | Dole_2857 | Dole_2989 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.402 |
| Dole_2857 | rpsT | Dole_2857 | Dole_2436 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.543 |
| Dole_2857 | topA | Dole_2857 | Dole_2445 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.588 |
| Dole_2990 | Dole_1031 | Dole_2990 | Dole_1031 | TIGRFAM: CRISPR-associated protein Cas2; KEGG: csa:Csal_0233 CRISPR-associated protein, Cas2. | Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.692 |
| Dole_2990 | Dole_3207 | Dole_2990 | Dole_3207 | TIGRFAM: CRISPR-associated protein Cas2; KEGG: csa:Csal_0233 CRISPR-associated protein, Cas2. | PFAM: histone family protein DNA-binding protein; KEGG: pca:Pcar_1455 integration host factor, beta subunit; Belongs to the bacterial histone-like protein family. | 0.692 |
| Dole_2990 | cas1 | Dole_2990 | Dole_2989 | TIGRFAM: CRISPR-associated protein Cas2; KEGG: csa:Csal_0233 CRISPR-associated protein, Cas2. | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.999 |
| Dole_3205 | Dole_3206 | Dole_3205 | Dole_3206 | PFAM: PSP1 domain protein; KEGG: pth:PTH_0064 uncharacterized homolog of PSP1. | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: gsu:GSU2230 DNA polymerase III, delta prime subunit. | 0.847 |
| Dole_3205 | Dole_3207 | Dole_3205 | Dole_3207 | PFAM: PSP1 domain protein; KEGG: pth:PTH_0064 uncharacterized homolog of PSP1. | PFAM: histone family protein DNA-binding protein; KEGG: pca:Pcar_1455 integration host factor, beta subunit; Belongs to the bacterial histone-like protein family. | 0.767 |
| Dole_3205 | lptD | Dole_3205 | Dole_3208 | PFAM: PSP1 domain protein; KEGG: pth:PTH_0064 uncharacterized homolog of PSP1. | Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | 0.495 |
| Dole_3205 | metG | Dole_3205 | Dole_3204 | PFAM: PSP1 domain protein; KEGG: pth:PTH_0064 uncharacterized homolog of PSP1. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.805 |
| Dole_3205 | topA | Dole_3205 | Dole_2445 | PFAM: PSP1 domain protein; KEGG: pth:PTH_0064 uncharacterized homolog of PSP1. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.516 |
| Dole_3206 | Dole_3205 | Dole_3206 | Dole_3205 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: gsu:GSU2230 DNA polymerase III, delta prime subunit. | PFAM: PSP1 domain protein; KEGG: pth:PTH_0064 uncharacterized homolog of PSP1. | 0.847 |