Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Dole_3207PFAM: histone family protein DNA-binding protein; KEGG: pca:Pcar_1455 integration host factor, beta subunit; Belongs to the bacterial histone-like protein family. (91 aa)    
Predicted Functional Partners:
Dole_1031
Histone family protein DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
 
 
0.980
Dole_2857
Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
 
 
 0.823
Dole_3206
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: gsu:GSU2230 DNA polymerase III, delta prime subunit.
  
  
 0.770
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
   0.764
Dole_3205
PFAM: PSP1 domain protein; KEGG: pth:PTH_0064 uncharacterized homolog of PSP1.
       0.757
Dole_2990
TIGRFAM: CRISPR-associated protein Cas2; KEGG: csa:Csal_0233 CRISPR-associated protein, Cas2.
    
 
 0.621
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
    
 
 0.614
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
 
 0.606
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.597
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
     
 0.544
Your Current Organism:
Desulfococcus oleovorans
NCBI taxonomy Id: 96561
Other names: D. oleovorans Hxd3, Desulfobacteirum oleovorans Hxd3, Desulfococcus oleovorans Hxd3, delta proteobacterium Hxd3, sulfate-reducing bacterium Hxd3
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