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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)    
Predicted Functional Partners:
TXNIP
Thioredoxin interacting protein.
    
 0.999
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.978
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.970
TXNRD1
Thioredoxin reductase 1.
   
 0.967
TXN2
Thioredoxin 2.
  
0.965
MSRA
Methionine sulfoxide reductase A.
  
 0.940
RRM1
Ribonucleotide reductase catalytic subunit M1.
  
 
 0.908
TXNRD2
Thioredoxin reductase 2.
   
 0.900
RRM2B
Ribonucleotide reductase regulatory TP53 inducible subunit M2B.
   
 
 0.895
RRM2
Ribonucleotide reductase regulatory subunit M2.
   
 
 0.886
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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