| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APP | CASP3 | ENSMPUP00000000998 | ENSMPUP00000010994 | Amyloid beta precursor protein. | Caspase 3; Belongs to the peptidase C14A family. | 0.849 |
| APP | CDK5 | ENSMPUP00000000998 | ENSMPUP00000008272 | Amyloid beta precursor protein. | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | 0.649 |
| APP | GSK3B | ENSMPUP00000000998 | ENSMPUP00000008296 | Amyloid beta precursor protein. | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.706 |
| APP | M3Y830_MUSPF | ENSMPUP00000000998 | ENSMPUP00000007487 | Amyloid beta precursor protein. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.653 |
| APP | M3Z596_MUSPF | ENSMPUP00000000998 | ENSMPUP00000018758 | Amyloid beta precursor protein. | Alpha-synuclein; Belongs to the synuclein family. | 0.955 |
| APP | MAPT | ENSMPUP00000000998 | ENSMPUP00000008060 | Amyloid beta precursor protein. | Microtubule-associated protein. | 0.958 |
| CASP3 | APP | ENSMPUP00000010994 | ENSMPUP00000000998 | Caspase 3; Belongs to the peptidase C14A family. | Amyloid beta precursor protein. | 0.849 |
| CASP3 | CDK5 | ENSMPUP00000010994 | ENSMPUP00000008272 | Caspase 3; Belongs to the peptidase C14A family. | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | 0.547 |
| CASP3 | GSK3B | ENSMPUP00000010994 | ENSMPUP00000008296 | Caspase 3; Belongs to the peptidase C14A family. | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.542 |
| CASP3 | M3Z596_MUSPF | ENSMPUP00000010994 | ENSMPUP00000018758 | Caspase 3; Belongs to the peptidase C14A family. | Alpha-synuclein; Belongs to the synuclein family. | 0.602 |
| CASP3 | MAPK1 | ENSMPUP00000010994 | ENSMPUP00000003112 | Caspase 3; Belongs to the peptidase C14A family. | Mitogen-activated protein kinase. | 0.933 |
| CASP3 | MAPT | ENSMPUP00000010994 | ENSMPUP00000008060 | Caspase 3; Belongs to the peptidase C14A family. | Microtubule-associated protein. | 0.984 |
| CASP3 | TUBB6 | ENSMPUP00000010994 | ENSMPUP00000004469 | Caspase 3; Belongs to the peptidase C14A family. | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. | 0.469 |
| CDK5 | APP | ENSMPUP00000008272 | ENSMPUP00000000998 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | Amyloid beta precursor protein. | 0.649 |
| CDK5 | CASP3 | ENSMPUP00000008272 | ENSMPUP00000010994 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | Caspase 3; Belongs to the peptidase C14A family. | 0.547 |
| CDK5 | GSK3B | ENSMPUP00000008272 | ENSMPUP00000008296 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.896 |
| CDK5 | M3Y830_MUSPF | ENSMPUP00000008272 | ENSMPUP00000007487 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.801 |
| CDK5 | MAPT | ENSMPUP00000008272 | ENSMPUP00000008060 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | Microtubule-associated protein. | 0.996 |
| GSK3B | APP | ENSMPUP00000008296 | ENSMPUP00000000998 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Amyloid beta precursor protein. | 0.706 |
| GSK3B | CASP3 | ENSMPUP00000008296 | ENSMPUP00000010994 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Caspase 3; Belongs to the peptidase C14A family. | 0.542 |
