MAP1LC3A protein (Mustela putorius) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

MAP1LC3A

Microtubule associated protein 1 light chain 3 alpha. (176 aa)

Predicted Functional Partners:

NBR1

0.990

FUNDC1

0.958

SQSTM1

0.948

ATG7

0.904

ATG4B

0.872

KEAP1

0.846

MAP1LC3C

0.837

ATG12

0.830

ATG5

0.821

GABARAPL2

0.821

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG4B	ENSMPUP00000000771	ENSMPUP00000000184	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.767
ATG12	ATG5	ENSMPUP00000000771	ENSMPUP00000009457	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG7	ENSMPUP00000000771	ENSMPUP00000017062	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.999
ATG12	FUNDC1	ENSMPUP00000000771	ENSMPUP00000012825	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	FUN14 domain containing 1.	0.652
ATG12	GABARAPL2	ENSMPUP00000000771	ENSMPUP00000009819	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor associated protein like 2.	0.970
ATG12	MAP1LC3A	ENSMPUP00000000771	ENSMPUP00000017703	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule associated protein 1 light chain 3 alpha.	0.830
ATG12	MAP1LC3C	ENSMPUP00000000771	ENSMPUP00000015608	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule associated protein 1 light chain 3 gamma.	0.763
ATG12	NBR1	ENSMPUP00000000771	ENSMPUP00000009707	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	NBR1 autophagy cargo receptor.	0.777
ATG12	SQSTM1	ENSMPUP00000000771	ENSMPUP00000000647	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Sequestosome 1.	0.836
ATG4B	ATG12	ENSMPUP00000000184	ENSMPUP00000000771	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.767
ATG4B	ATG5	ENSMPUP00000000184	ENSMPUP00000009457	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.766
ATG4B	ATG7	ENSMPUP00000000184	ENSMPUP00000017062	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.798
ATG4B	GABARAPL2	ENSMPUP00000000184	ENSMPUP00000009819	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	GABA type A receptor associated protein like 2.	0.980
ATG4B	MAP1LC3A	ENSMPUP00000000184	ENSMPUP00000017703	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Microtubule associated protein 1 light chain 3 alpha.	0.872
ATG4B	MAP1LC3C	ENSMPUP00000000184	ENSMPUP00000015608	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Microtubule associated protein 1 light chain 3 gamma.	0.787
ATG4B	NBR1	ENSMPUP00000000184	ENSMPUP00000009707	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	NBR1 autophagy cargo receptor.	0.431
ATG4B	SQSTM1	ENSMPUP00000000184	ENSMPUP00000000647	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Sequestosome 1.	0.538
ATG5	ATG12	ENSMPUP00000009457	ENSMPUP00000000771	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG5	ATG4B	ENSMPUP00000009457	ENSMPUP00000000184	Autophagy protein 5; Involved in autophagic vesicle formation.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.766
ATG5	ATG7	ENSMPUP00000009457	ENSMPUP00000017062	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.995